Individual Dose Response and Radiation Origin of Childhood and Adolescent Thyroid Cancer in Fukushima, Japan

Individual Dose Response and Radiation Origin of Childhood and Adolescent Thyroid Cancer in Fukushima, Japan

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for


A: Good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good


Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good


Comments: The Discussion illustrates the association between radiation exposure from the nuclear accident and the increased dose of thyroid cancer. It further described the proportional increase of relative risk (RR) of thyroid cancer in individual dose groups providing relevant literature. The Discussion gives a clear view of the cause of the high incidence rates of thyroid cancer in the 2nd round of cancer study. The Conclusion presents the study of thyroid cancer in Fukushima residents exposed at ≤18 years of age and demonstrated a linear relationship between thyroid cancer incidence and individual external dose. Lastly, the authors suggest the dominant cause of increased childhood thyroid cancer in Fukushima.



Q: Does the author utilize relevant literature?

A: Good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good


Writing style

Q: Is it clear and understandable?

A: Good


Comments: There are few errors found in the manuscript, which are as follows:

·       Under Discussion, 3rd paragraph, 4th sentence, “High incidence rates in the 2nd round… 1st round, indicated that the increased thyroid cancer…” should be written as “High incidence rates in the 2nd round… 1st round indicating that the increased thyroid cancer…”.

·       Under Discussion, 6th paragraph, 2nd sentence, “Radiation related thyroid cancer occurred mostly in children and adolescents…” should be “Radiation-related thyroid cancer occurs mostly in children and adolescents…”.


Further comments on the paper

Comments: The manuscript provides a detailed analysis of the individual dose-response and radiation origin of childhood and adolescent thyroid cancer in Fukushima, Japan. The probable radiation origin of childhood thyroid cancer in Fukushima after the nuclear accident was examined from the cancer registry in Japan, and the age distribution of thyroid cancer cases as compared with the Chernobyl cases. The methods of the study include Thyroid ultrasound screening and study subjects, Dose estimation and the dose-response of the thyroid cancer incidence proportion.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Science Repository Team 


Author Info

Corresponding Author
Toshiko Kato
Independent Researcher, Nara, Japan

Article Info

Article Type
Research Article
Publication history
Received: Sat 02, Apr 2022
Accepted: Mon 18, Apr 2022
Published: Wed 04, May 2022
© 2023 Toshiko Kato. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2022.02.02