Low Prognostic Nutritional Index Indicates Dismal Prognosis in Patients with Diffuse Large B Cell Lymphoma

Review Data

Purpose and Significance of Study: This study attempted to explore the prognostic value of baseline prognostic nutritional index (PNI) in diffuse large B cell lymphoma (DLBCL), which does not yet exist in the literature. The results show that PNI is a simple and useful marker to predict survival outcome in DLBCL patients, and low PNI is an independent predictor of a better outcome in terms of event-free survival and overall survival in DLBCL, suggesting that PNI is an effective prognostic factor in patients with DLBCL.

 

Fit with Scope of Journal: The manuscript is of very high interest for the journal Clinical Oncology and Research.

The manuscript has some minor errors (already corrected in the galley proof), which are listed below –

 

The common errors are –

·       Omission of articles, e.g., “a” before “worse” in the 1^st sentence of Results in the Abstract, “an” before “aggressive” in the 3^rd sentence of the 1^st paragraph of the Introduction, and so on.

·       Omission of “,”, e.g., after “DLBCL patients” in the 1^st sentence of Conclusion in the Abstract, after “DLBCL patients” in the 3^rd sentence of the 1^st paragraph of the Introduction, and so on.

·       “Extranodal” must always be written without hyphen to maintain consistency.

·       Words like “cut-off”, “p-value”, “antibody-dependent”, “cancer-related” and “event-free” must be hyphenated in all places to maintain consistency.

The errors are –

 

In the Abstract –

  Under Results –

·       In the last sentence, “the” at the start and “to be” must be removed.

In the Introduction –

  In the 1^st paragraph –

·       In the 1^st sentence, “for” after “constituting” must be removed.

·       In the 2^nd sentence, “,” after “disease” must be removed.

·       In the 3^rd sentence, “,” before “yet” must be replaced with “;”, and “would” must be replaced with “still”.

·       In the 4^th sentence, “to” after “important” must be replaced with “for”.

·       In the last sentence, “pose” must be replaced with “poses”.

  In the 3^rd paragraph –

·       In the 1^st sentence, “researches” must be replaced with “pieces of research”.

·       In the 2^nd sentence, “a” before “promptly” and “along with” must be removed, and “,” must be inserted after “symptoms”.

·       In the 4^th sentence, “for” before “DLBCL” must be replaced with “of”.

In the Patients and Methods –

  Under Patients and treatment –

·       In the 4^th sentence, “,” after “therapy” must be removed.

  Under Data gathering –

·       In the last sentence, “,” after “records” must be removed.

  Under Statistical analysis –

·       In the 6^th sentence, “by” before “using” must be removed.

In the Results –

  Under Identification of the optimal cut-off value for PNI –

·       In the 2^nd sentence, “of” after “median” must be removed.

·       In the last sentence, “divided” must be replaced with “categorized”.

  Under Survival analysis –

  In the 3^rd paragraph –

·       In the 1^st sentence, with the last set of parenthesis, “adjust” must be replaced with “adjusted” both times.

In the Discussion –

  In the 1^st paragraph –

·       In the 3^rd sentence, “barrier” must be replaced with “barriers”.

·       In the 4^th sentence, “biomarker” must be replaced with “biomarkers”.

  In the 2^nd paragraph –

·       In the 2^nd sentence, “,” after “regimen” must be removed.

·       In the 3^rd sentence, “difference” must be replaced with “differences”.

·       In the 4^th sentence, “2” must be replaced with “two”.

  In the 3^rd paragraph –

·       In the 6^th sentence, “the” and “and” must be removed.

·       In the 9^th sentence, “are” must be replaced with “is”, and “being” must be inserted before “applied”.

  In the 4^th paragraph –

·       In the 3^rd sentence, “the” before “nutritional status” must be removed.

·       In the 6^th sentence, “are” must be replaced with “is”.

·       In the 7^th sentence, “a” before “research” must be removed.

Author Info

Baoan Chen Chunyan Luan Jing Zhang Xue Wu

Corresponding Author

Baoan Chen
Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu Province, China

Article Info

Article Type

Research Article

Publication history

Received: Fri 17, Apr 2020
Accepted: Mon 04, May 2020
Published: Fri 08, May 2020

Copyright

© 2023 Baoan Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.05.01