Mucosal Bacterial Immunotherapy in Solid Organ Recipients with Recurrent Respiratory Tract Infections: Case Report

Author Info

Javier Carbone Marisa di Natale Magdalena Salcedo Mario Romero Rosalia Laporta María Carreño Elizabeth Sarmiento

Corresponding Author

Javier Carbone
Clinical Immunology Department, Hospital General Universitario Gregorio Marañon, Madrid, Spain

A B S T R A C T

Bacterial infections are the most frequent infectious complications among solid organ recipients. These complications are associated with a high morbidity and mortality, despite recent advances in antimicrobial prophylaxis in the transplant setting. New therapeutic modalities are warranted. We present here a retrospective study based on medical records review of 2 solid organ recipients that were treated with mucosal bacterial immunotherapy because of recurrent bacterial respiratory infections long time after transplantation. A successful decrease of the frequency of bacterial respiratory infections during a period of up to 8 years was observed in one of the patients. We suggest that clinical trials in this field are warranted.

Article Info

Article Type

Case Report

Publication history

Received: Mon 30, Nov 2020
Accepted: Thu 10, Dec 2020
Published: Thu 24, Dec 2020

Copyright

© 2023 Javier Carbone. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.TCR.2020.02.07