Aggressive Adult Pancreatoblastoma with Early Recurrence: A Case Report

Author Info

Martina Nebbia Silvia Uccella Silvia Carrara Silvia Bozzarelli Francesca Gavazzi Cristina Ridolfi Giovanni Capretti Gennaro Nappo Michele Pagnanelli Alessandro Zerbi

Corresponding Author

Martina Nebbia
Pancreatic Surgery Unit, Humanitas Research Hospital IRCCS, Via Manzoni, Rozzano, Milan, Italy

A B S T R A C T

Background: Pancreatoblastoma (PB) is a rare malignant epithelial tumor of the pancreas, mainly occurring in pediatric population. Pancreatoblastoma of the adult is extremely rare and usually shows a more aggressive biological behavior and a worse prognosis. Case Presentation: The patient was a 54-year-old man admitted for abdominal pain and weight loss. A computed tomography (CT) scan showed a 12 cm heterogeneous hypoattenuating mass in the pancreatic head. An endoscopic ultrasound-guided biopsy suggested the diagnosis of pancreatoblastoma (PB). The patient underwent a pancreaticoduodenectomy (PD) combined with limited liver resections for intraoperative finding of multiple liver metastasis. Pathological findings confirmed the diagnosis of PB metastatic to the liver. The tumor recurred in the liver 5 months after surgery and the patient succumbed due to tumor dissemination 8 months after initial diagnosis. Conclusion: Adult pancreatoblastoma is a rare pancreatic neoplasm with malignant behavior. The aim of this manuscript is to report our experience with pancreatoblastoma in the adult and to contribute improving knowledge about the clinical behavior of this rare and aggressive malignancy.

Article Info

Article Type

Case Report

Publication history

Received: Thu 20, Jul 2023
Accepted: Mon 28, Aug 2023
Published: Mon 02, Oct 2023

Copyright

© 2023 Martina Nebbia. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2023.05.02