Biochemical and Molecular Diagnostic Indicators for Cancer

Author Info

N. Baskaran S Vignesh V Chandrasekar

Corresponding Author

N. Baskaran
Department of Food Processing Business Incubation Center, Indian Institute of Food Processing Technology (IIFPT), Tamil Nadu, India

A B S T R A C T

Biomarkers are substances that are either secreted by the tumor or produced by the body in response to the presence of cancer. Biomarkers serve as an objective measure for evaluation of normal and pathological processes as well as pharmacological responses to a therapeutic intervention. Cancer studies are usually difficult to interpret, especially based on the contemporary medical diagnosis. In this circumstance, biomarkers are developing as reliable diagnostic metabolites, which have many promising applications in oncological screening, differential diagnosis, risk assessment, response to treatment, and examining the progression of disease. Genome or protein based prognostic biomarkers are available, for numerous cancer types, for potential inclusion into clinical prognostic staging methods. However, there lies difficulty in translating these biomarkers into clinical outcomes. This review concerns important biomarkers related to wide varieties of cancer and also elucidates mode of action of few major biomarkers.

Article Info

Article Type

Review Article

Publication history

Received: Mon 15, Feb 2021
Accepted: Sat 02, Oct 2021
Published: Fri 15, Oct 2021

Copyright

© 2023 N. Baskaran. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2021.08.11