Management and Outcomes of Spontaneous Rupture of Hepatocellular Carcinoma: Current Practice

Author Info

Ahmad Mirza Arslan Pannu Eloise Lawrence Ghulam Murtaza Dar Khurram Khan Salman Jabbar Shahzad Ahmed

Corresponding Author

Ahmad Mirza
Department of Abdominal Transplant and Hepato-Biliary Surgery, University of Cincinnati Medical Center, Ohio, USA

A B S T R A C T

Objectives: To review the current management options for ruptured hepatocellular carcinoma (HCC) at acute presentation and assess the impact of each treatment modality on short- and long-term patient related outcome. Study design: A PubMed search was undertaken for review articles from 1950 to 2019 using key phrases “Ruptured hepatocellular carcinoma”, “trans-arterial embolization”, “resection”, “computed tomographic scan” and “conservative management”. Further manual search was performed to identify key articles from the reference list. Methodology: All papers with previous described management for ruptured HCC were reviewed. The morbidity, mortality and comparison of various management options were reviewed. Current practice guidelines were visited to identify common practice protocols. Conclusion: Ruptured HCC is associated with significant morbidity and mortality. Multiple management options can be applied guiding by patient’s overall condition. Conservative management is associated with overall poor outcome. Staged liver resection is associated with better outcome with improved morbidity and mortality.

Article Info

Article Type

Research Article

Publication history

Received: Tue 05, Nov 2019
Accepted: Tue 19, Nov 2019
Published: Thu 28, Nov 2019

Copyright

© 2023 Ahmad Mirza. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2019.06.04