A Case of Double Primary Carcinoma was Accidentally Found During Operation: Hepatocellular Carcinoma and Appendiceal Mucinous Adenocarcinomas

Review Data

Q: Is the topic relevant to the journal area of interest?

Comments: Yes, the topic is relevant to the journal area of interest.

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

Comments: The abstract contains the following components typically expected in a medical case report abstract.
The keywords "Synchronous double primary cancer," "hepatocellular carcinoma," and "appendiceal mucinous adenocarcinomas" appear to be appropriately chosen and align with the content of the case report.

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

Comments: The paper follows a structured format commonly found in medical case reports, including sections such as Background, Case Presentation, Treatment, Discussion, and Conclusion. This structure is generally coherent with the goal of presenting a detailed case study of a rare and complex medical condition involving synchronous double primary cancers of hepatocellular carcinoma (HCC) and appendiceal mucinous adenocarcinomas. The sections are logically organized to provide a comprehensive overview of the patient's case, diagnostic challenges, treatment, and outcome.

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

Comments: The "Discussion" and "Conclusion" sections of the case report are related to the results and findings presented in the preceding sections, and they are generally coherent with the rest of the paper.

Literature

Q: Does the author utilize relevant literature?

Comments: Yes, the author utilizes relevant literature to support the information provided in the case report.

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

Comments: The length of the paper appears to be adequate for the topic.

Reducing the length could potentially remove important information and compromise the value of the case report.

Writing style

Q: Is it clear and understandable?

A: Yes, the text provided is clear and understandable. The author uses medical terms appropriately and explains them in a way that makes the content accessible to a broad audience.

Further comments on the paper

Comments:
The case report presents a rare and unique clinical scenario involving synchronous double primary cancer of hepatocellular carcinoma (HCC) and appendiceal mucinous adenocarcinomas. Such cases are inherently interesting and valuable for the medical literature due to their rarity.

1.     Detailed Clinical Information: The paper provides a comprehensive account of the patient's medical history, physical examination, laboratory results, imaging studies, surgical procedures, pathology findings, and follow-up. This level of detail is essential for understanding the complexity of the case.

2.     Clinical Relevance: The report emphasizes the clinical relevance of the case by discussing the diagnostic challenges and the need for careful preoperative evaluation and intraoperative exploration. It underscores the importance of considering multiple primary cancers in clinical practice.

3.     Clear Imaging: The use of imaging studies, including B-ultrasound, CT, and MRI, adds to the clarity of the presentation and helps readers visualize the patient's condition. The inclusion of images enhances the comprehensibility of the report.

4.     Thorough Pathological Information: The detailed description of the pathology findings, including immunohistochemical results, adds depth to the case report and aids in the understanding of the patient's condition.

5.     Awareness and Learning Opportunity: The paper serves as an educational tool, raising awareness among clinicians and researchers about the existence of such rare synchronous double primary cancers. It encourages healthcare professionals to consider comprehensive diagnostic approaches.

6.     Clinical Implications: While brief, the conclusion does emphasize the need for standardized treatment approaches in such cases, which can serve as a starting point for further discussion and research in the field.

Overall, the case report offers valuable insights into a rare clinical scenario and highlights the need for careful diagnosis and management in complex cases involving multiple primary cancers.

Q: Would you recommend this manuscript for further publication?

A: Yes - This manuscript is recommended for further publication

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team