A Rare Case of Metastatic Mucinous Breast Carcinoma as a First Presentation of Colon Cancer in a Male Patient: Case Report and Review of the Literature

Review Data

Reviewer’s Note:

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion explains the extreme rarity of the case and places it in context. It also highlights the rationale of the diagnostic approach adopted and provides suggestions for the general management of mucinous breast cancer.

Q: Does the author utilize relevant literature?

A: Good

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Q: Is it clear and understandable?

A: Good

Any comments:

This rare case reports a metastatic mucinous breast carcinoma of colon cancer origin with asymptomatic gastrointestinal tract in a 61-year-old male patient. This is the first case of a male patient who presented with a breast lesion with primary descending colon tumor that was identified during patient workup. This further illustrates that metastatic breast tumor in some cases is misinterpreted clinically as primary breast tumor and it is important to differentiate primary breast cancer from a metastatic breast cancer of colonic origin. Due to the rarity of this case, when diagnosed in male patient, the required immunohistochemical strains must be performed, and proper investigations of the abdomen and GI tract must be carried out.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Thanks,
Science Repository Team