Validation of PI-RADS v2 Scores at Various Non-University Radiology Practices

Validation of PI-RADS v2 Scores at Various Non-University Radiology Practices

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for


A: Very good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good


Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Very good



This study compares the differences in Prostate Imaging Reporting and Data System (PI-RADS v2) scoring across different institutions for the cases that were referred for targeted biopsy. The study is well designed and executed. The Methods and Results are adequately described. The Results provide further evidence that PI-RADS v2 will need further improvement in order to improve positive biopsy rate so as to avoid much of the un-necessary biopsy that occurs in PI-RADS 3 lesions. The Discussion offers a thorough and detailed analysis of the findings of the present study taking all the relevant literature into account. The study is well supported with briefly explained tables. It finally Concludes that PI-RADS v2 scoring can serve as a valuable tool in aiding decision making for prostate lesions that are amenable to biopsy.



Q: Does the author utilize relevant literature?

A: Very good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good


Writing style

Q: Is it clear and understandable?

A: Very good


Further comments on the paper

Comments: This retrospective study aims to assess the validity of Prostate Imaging Reporting and Data System (PI-RADS v2) scores in a non-university practice setting where the practitioners and the referring urologists and radiologists are not associated with university academic center. The study evaluates the efficacy of PI-RADS v2 scoring at predicting positive biopsy rates for in-bore MRI-guided targeted biopsy. The study holds significance as it shows that PI-RADS v2 can be applied homogeneously in the non-university setting without significant difference in outcome. The retrospective nature of the study carrying inherent risk for selection bias, the small sample size of the study in comparison to related literature and the specialized nature of the institution come out as some of the limitations of the study.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team


Author Info

Corresponding Author
John C. Chang
Department of Radiology, Banner MD Anderson Cancer Center, Gilbert, Arizona, USA

Article Info

Article Type
Research Article
Publication history
Received: Thu 09, Dec 2021
Accepted: Mon 27, Dec 2021
Published: Wed 29, Dec 2021
© 2023 John C. Chang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.ACO.2021.02.02