Topical and Capsular RM Diabetes Wound Cure for Treatment of Diabetic Foot Ulcer

Author Info

George Uchenna Eleje Chidiebele Malachy Ezeude Celestine Ogonna Oguejiofor Charlotte Blanche Oguejiofor Iffiyeosuo Dennis Ake Patrick Maxwell Uche Ifeoma Clara Ajuba Chinyelu Uchenna Ufoaroh Ekene Agatha Emeka Arinze Anthony Onwuegbuna Chisom God’swill Chigbo Kindness Chidi Irikannu Ekeuda Uchenna Nwankwo

Corresponding Author

George Uchenna Eleje
Effective Care Research Unit, Department of Obstetrics and Gynaecology, Nnamdi Azikiwe University, Nnewi campus, Nigeria

A B S T R A C T

Background: Despite the prevalence and quality of life impact of diabetic foot ulcer (DFU), novel topical and oral therapy standard-of-care remain an important research priority. To date, the lack of available data has made it difficult to assess the efficacy of topical and capsular RM diabetes wound cure for DFUs. Case Presentation: We report the case of a 59-year-old Nigerian woman P2+0 with 2 living children, a known diabetes mellitus patient since 2006 and has been compliant with her antidiabetic medications, who presented with complaint of right foot ulcer. We also report the case of a 69-year-old Nigerian man that presented with DFU. The latter is a known diabetic and hypertensive diagnosed 15 years prior to presentation. For the first case, both topical and capsular RM wound cure were applied twice daily over an area of the ulcer for 8 weeks. For the second case, only RM diabetes wound cure capsule applied twice daily was received for 8 weeks. Efficacy was analysed by lesion measurements and photographs to determine overall response rate (ORR), and complete response (CR). All doses were well tolerated, and potentially efficacious. At 8 weeks across all dose levels, subjects achieved 100.0% ORR and 50.0% CR. Conclusion: Application of topical and ingestion of the oral capsule of RM diabetes wound cure appear safe and well tolerated with some reduction in lesion pain. Some greater levels of lesion stabilization was observed in the subjects, and this demonstrated great clinical benefit in foot ulcers. A randomized, placebo-controlled trial to confirm these findings is recommended.

Article Info

Article Type

Case Report and Review of the Literature

Publication history

Received: Wed 10, Aug 2022
Accepted: Mon 22, Aug 2022
Published: Fri 09, Sep 2022

Copyright

© 2023 George Uchenna Eleje. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2022.09.04