A Survival Analysis of Chinese Patients with Gastrointestinal Mucosal Melanomas: A Single-Centre Retrospective Study

Author Info

Jiayao Huang Junrong Chen Xiaoying Lou Yi Lu Jiayin Yao Manxia Lin Jiachen Sun

Corresponding Author

Manxia Lin
Department of Ultrasound, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

A B S T R A C T

Aim: Mucosal melanomas are highly malignant tumors that are of great interest for their aggressive behaviour and unfavourable prognosis, which could be the result of many reasons. In this paper, we describe a retrospective study performed to investigate the characteristics and prognoses of gastrointestinal mucosal melanomas in a Chinese population to help future clinicians recognize the prognosis of this disease. Methods: We retrospectively studied 49 patients diagnosed with gastrointestinal mucosal melanomas. Multivariate analysis of prognosis and overall survival (OS) was performed using the Cox proportional hazards model. Results: The multivariate analysis showed that the condition of the primary or metastatic tumor and tumor location were independent factors that affected the prognosis of patients with gastrointestinal mucosal melanomas. Patients with metastatic tumors had a better prognosis than patients with primary tumors, and tumors that occurred in the lower gastrointestinal tract had a better prognosis than those that occurred in the upper gastrointestinal tract. Conclusion: Tumor location and the condition of the primary or metastatic tumor may be independent factors that affect the prognosis of patients with gastrointestinal mucosal melanomas.

Article Info

Article Type

Research Article

Publication history

Received: Thu 10, Jun 2021
Accepted: Wed 23, Jun 2021
Published: Thu 15, Jul 2021

Copyright

© 2023 Manxia Lin. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2021.07.04