Mediastinal Lymphangiohemangioma: A Case Report and Review of the Literature with Focus on the Ambiguous Nomenclature

Author Info

Candice C. Black Harvinder S Jagait Jesse S Bond Julianna M Czum

Corresponding Author

Candice C. Black
Department of Pathology and Laboratory Medicine

A B S T R A C T

The benign mediastinal vascular lesion is an area in medicine with ambiguous terminology and poor interand intra-disciplinary agreement. Lymphangiohemangioma of the mediastinum is a rare, benign entity with few previous reports in the US literature. We present a case of a 55-year-old woman with shortness of breath and chest pain who was found to have an anterior mediastinal mass on imaging. The MRI features favored a mediastinal hemangioma with a differential diagnosis that included thymoma. The multilobulated mass was surgically removed however the left phrenic nerve was sacrificed during the resection. Histologically the lesion consisted of dilated vascular spaces of varying sizes with intra-luminal, calcified phleboliths. A variety of equivocal diagnostic terms were considered for a benign, mediastinal vascular lesion. Subsequent immunohistochemistry (IHC) showed the vessel lining consisted of both vascular and lymphatic endothelium therefore the final diagnosis made was mediastinal lymphangiohemangioma.

Article Info

Article Type

Case Report

Publication history

Received: Mon 31, Dec 2018
Accepted: Fri 08, Feb 2019
Published: Wed 27, Feb 2019

Copyright

© 2023 Candice C. Black. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2019.01.005