p38 MAP Kinase-Mediated Odontogenic Differentiation of Dental Pulp Stem Cells
Purpose and Significance of Study: This study investigated the role of p38 mitogen-activated protein kinase under normal and oxygen-deprived conditions to reveal its effect on odontogenic dental pulp stem cell differentiation. p38 and oxygen level were identified as crucial factors, thus indicating their potentially essential roles in the design of successful pulp-dentin complex engineering strategies for the regeneration of damaged teeth.
Fit with Scope of Journal: The manuscript is of very high interest for the journal International Journal of Regenerative Medicine.
The discussion aptly dissected the findings of this study referring to the results of the other relevant studies in the past and laid down the future implications.
o The manuscript contains a few minor errors (already corrected in the galley proof), which are listed below –
· In the 1st sentence of Alizarin Red Staining under Methods, “paraformaldehyde” is misspelled.
· Omission of articles, e.g., “the” before “cultural” in the 1st sentence of the 2nd paragraph in the Introduction, before “natural” in the 4th sentence of the same paragraph, and so on.
· Omission of “,”, e.g., after “studies” and “ours” in the 3rd sentence of the 1st paragraph of the Introduction, after “environments” and “contact” in the 2nd sentence of the 2nd paragraph in the Introduction, and so on.
Department of Oral Biology, University of Illinois at Chicago, Chicago, Illinois , USA
Received: Thu 28, May 2020
Accepted: Wed 10, Jun 2020
Published: Fri 03, Jul 2020
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