Incidentally Detected Asymptomatic Thrombus in the Inferior Vena Cava Thought to be Caused by Central Venous Catheterization for an Oral Surgical Procedure

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion offers a clear and apt analysis of the present case. The authors suggest that it may be necessary to examine for the presence or absence of thrombus in the inferior vena cava with blood tests or diagnostic imaging before removal of the CV catheter, especially in cases in which the patient has several pathological and surgical factors increasing the likelihood of thrombosis as an asymptomatic inferior vena cava thrombosis coming off from the vascular wall may be fatal for the patient.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This is the report of an accidental detection of asymptomatic thrombus in the inferior vena cava possibly caused by central venous catheterization for orofacial surgery. The extent of the relationship between the formation of the thrombus and the insertion of the catheter via the left femoral vein in the present case is unclear. Also, it is difficult to rule out the possibility that thrombosis was present preoperatively because contrast-enhanced CT was not performed before insertion of the CV catheter in this case. However, the effectiveness of anticoagulant therapy for the thrombus suggested that it was not old but fresh thrombosis.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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