ECMO Cannulation Criteria in COVID-19 (ECC-VID) and Obesity: A Literature Review and Retrospective Cohort Analysis

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The Discussion gives an overview of the cohort study undertaken to show the efficiency of ECMO cannulation among COVID-19 and obese patients providing relevant literature. Moving forward, the Discussion highlights the limitations of the study conducted. Lastly, it suggests that the utilization of ECMO for COVID-19 patients associated with acute respiratory distress syndrome (ARDS), subsets should be considered, and outcomes should be further investigated.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Comments: There are few errors found in the manuscript which are as follows:

·       In Introduction, 2^nd paragraph, 1^st sentence, Obese patients are at high risk … in motrality in critical ill obese patients” must be written as “Obese patients are at high risk … in mortality in critically ill obese patients”.

·       In Results, 1^st paragraph, 3^rd sentence, “Fifty five percent (n=11) were female, two of which were pregnant” can better be written as “Fifty-five percent (n=11) were female, two of whom were pregnant”.

·       In Discussion, 4^th paragraph, 2^nd sentence, “Our cohort not only contributes to the existing literature demonstrating a relatively low mortality in patients who receive ^d ECMO support … ARDS, but is hypothesis …” is rewritten as “Our cohort not only contributes to the existing literature demonstrating relatively low mortality in patients who received ECMO support … ARDS but hypothesis …”.

Further comments on the paper

Comments: The manuscript illustrates a retrospective cohort analysis of ECMO cannulation criteria in COVID-19 and obesity. The research further describes the importance of Veno-Venous Extracorporeal Membrane Oxygenation (V-V ECMO) in rescue therapy in patients with acute respiratory distress syndrome (ARDS). The findings of this research revealed high survival in hospital discharge and demonstrated non-inferior outcomes and survival in obese patients. The manuscript also discusses the methods used in the research and establishes retrospectively reviewed demographic, clinical, and diagnostic data obtained during each patient’s admission. The results and outcomes of the study are discussed thoroughly.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Thanks,
Science Repository Team