Small Cell Carcinoma of the Breast: A Report of 2 Cases and Literature Review

Small Cell Carcinoma of the Breast: A Report of 2 Cases and Literature Review

Author Info

Corresponding Author
Paige Aiello
Department of Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA


Two female patients were diagnosed with primary small cell carcinoma of the breast that was estrogen receptor, progesterone receptor, and Her-2 Neu negative. Diagnosis was made by ultrasound-guided core needle biopsy. They both underwent neoadjuvant chemotherapy. The first patient had negative sentinel lymph node biopsy and underwent postoperative whole breast radiation. She has remained disease-free. The second patient underwent preoperative radiation only, had one positive sentinel lymph node, and declined postoperative radiation. The second patient had metastasis to the axillary lymph nodes as well as recurrence. She was treated with chemotherapy, surgery, and radiation, but ultimately developed more diffuse metastasis. We discuss current literature regarding diagnosis, treatment, and prognosis in small cell carcinoma of the breast.

Article Info

Article Type
Case Report and Review of the Literature
Publication history
Received: Mon 13, Jun 2022
Accepted: Wed 29, Jun 2022
Published: Tue 12, Jul 2022
© 2021 Paige Aiello. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2022.07.02