Cholecystectomy for Resistant Metastatic Malignant Melanoma of the Gallbladder: A Case Report

Cholecystectomy for Resistant Metastatic Malignant Melanoma of the Gallbladder: A Case Report

Author Info

Corresponding Author
Maria Julia Corbetta Machado
John Hunter Hospital, Australia

A B S T R A C T

Malignant melanoma is an unpredictable disease, known to metastasize early even in thin melanomas. Historically the presence of intraabdominal metastasis meant poor prognosis with a 5-year survival of less than 20%. That has significantly changed with effective systemic therapy (EST), with most recent studies reporting 5-year survival of up to 50%. Metastasecectomy for resistant disease has been considered in Stage IV disease, however there is very little literature on the combination of EST and metastasectomy. This report describes a case of Stage IV malignant melanoma patient who developed resistant disease within her gallbladder fundic wall. She underwent open cholecystectomy, with complete metabolic response at 1-year follow up PET.

Article Info

Article Type
Case Report
Publication history
Received: Tue 21, Jan 2020
Accepted: Mon 10, Feb 2020
Published: Thu 20, Feb 2020
Copyright
© 2023 Maria Julia Corbetta Machado. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.IJSCR.2020.01.03