Is Microsatellite Instability Important in Response to Radiotherapy in Patients with Rectal Cancer?

Is Microsatellite Instability Important in Response to Radiotherapy in Patients with Rectal Cancer?

Author Info

Corresponding Author
Yasemin Benderli Cihan
Department of Radiation Oncology, Kayseri City Education and Research Hospital, Kocasinan/Kayseri, Turkey

A B S T R A C T

MSI is the indicator of a DNA repair error that may lead to mutation accumulation formed in the cell. Although there are conflicting studies in the literature, in many studies it has been revealed that MSI has predictive and prognostic effect on response to RT in rectal cancer.

Article Info

Article Type
Mini Review
Publication history
Received: Tue 30, Jun 2020
Accepted: Thu 30, Jul 2020
Published: Fri 14, Aug 2020
Copyright
© 2021 Yasemin Benderli Cihan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.IJCST.2020.01.03