Chronic Myeloid Leukemia (CML) as Surgical Emergency

Chronic Myeloid Leukemia (CML) as Surgical Emergency

Author Info

Corresponding Author
Anurag Mishra
Professor, Department of Surgery, Maulana Azad Medical College, New Delhi, India


Ileal perforation peritonitis is a critical surgical emergency often encountered in developing countries, commonly associated with typhoid fever, tuberculosis, trauma, and non-specific enteritis. This case report presents a unique instance of nonspecific enteritis associated with chronic myeloid leukemia (CML). A 16-year-old girl with a history of pulmonary tuberculosis presented with symptoms, leading to the diagnosis of ileal perforations and CML. Surgical intervention involved ileal resection and double barrel ileostomy. The postoperative course included complications and chemotherapy with imatinib, demonstrating the challenges and management strategies in such cases. The discussion emphasizes the varied aetiologies of non-traumatic ileal perforation in different regions and sheds light on the rare gastrointestinal manifestations of CML. Notably, this report underscores the significance of prompt imatinib therapy in controlling CML while highlighting the need for vigilant monitoring and dose adjustments due to chemotherapy-related adverse effects.

Article Info

Article Type
Case Report
Publication history
Received: Tue 26, Dec 2023
Accepted: Tue 13, Feb 2024
Published: Wed 13, Mar 2024
© 2023 Anurag Mishra. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.AJSCR.2024.01.02