Liver Transplantation in a Patient with 1p36 Deletion Syndrome

Author Info

Ashesh P. Shah Jonathan Fenkel Zachary E. Daitch

Corresponding Author

Jonathan Fenkel
Division of Gastroenterology and Hepatology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA

A B S T R A C T

1p36 deletion syndrome is a rare, genetic disorder often affecting neurological, cardiac, renal, and physical development, without a known associated liver manifestation. We present the case of a young woman with 1p36 deletion syndrome and chronic liver failure requiring liver transplant evaluation who subsequently went on to successfully undergo orthotopic liver transplantation. With multidisciplinary post-operative care, including developmentally appropriate rehabilitation and strong family support, >3-year posttransplant survival has been achieved. This case, the first reported liver transplant among patients with 1p36 deletion syndrome, suggests that liver transplantation can be safely performed in patients with this condition.

Article Info

Article Type

Case Report

Publication history

Received: Mon 23, Mar 2020
Accepted: Mon 20, Apr 2020
Published: Mon 27, Apr 2020

Copyright

© 2023 Jonathan Fenkel. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2020.04.05