Four Years Long-Term Follow-Up of Patient with Atypical Chronic Myeloid Leukemia Post Haploidentical Transplant with TBF Conditioning

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are the methods the author uses adequate and well-used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The study described atypical chronic myeloid leukemia (aCML) – a rare subtype of myelodysplastic syndrome/myeloproliferative neoplasm overlap syndromes. It also highlights that there is a scarcity of standard care methods. Further, it discusses the adverse prognostic factors of the disease. In Conclusion, the authors considered Allo-HSCT as the only curative choice for aCML. Lastly, it is also reported that due to the low incidence of the disease, no relevant data is available for haploidentical transplantation with PTCy.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: The manuscript illustrates four years of long-term follow-up of a patient with atypical chronic myeloid leukemia post haploidentical transplant with TBF conditioning. The authors emphasized the clinical presentations and diagnostic criteria of the disease. In addition, the report presented the condition of a 42-year-old man highlighting its relevant diagnoses and treatment methods.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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