Journal of Integrative Cardiology Open Access (ISSN 2674-2489)

NLM ID: 101769245 Journal Impact Factor: 1.46*

Journal of Integrative Cardiology Open Access is a peer-reviewed medical journal that focuses on a wide range of areas in this field including pulmonary, respiratory diseases related to respiratory system and treatment methods and creates a platform for the authors to make their contribution towards the journal and the editorial office promises a peer review process for the submitted manuscripts for the quality of publishing.

Journal of Integrative Cardiology Open Access is one of the best open access journals that aims to publish the most complete and reliable source of information on discoveries and current developments in the mode of original articles, review articles, case reports, short communications, etc. in the field and provide online access to the researchers worldwide without any restrictions or subscriptions.

Journal of cardiology emphasis on conceptual breakthroughs, its goal is to facilitate rapid publication and aimed to publish the clinical cases on various areas of heart related issues, cardiovascular medicine, cardiovascular diseases, myocardial infraction, atrial fibrillation, valvular heart diseases, cardiomyopathy, heart failure, coronary artery diseases, atherosclerosis, arrhythmias, angina, congenital heart diseases, pericardial disease, vascular diseases, hypertension, peripheral arterial disease, heart defects, paediatric cardiology, echocardiography, heart surgery and treatment. Cardiology images are also welcome for possible publication.

All the work at Science Repository is licensed under a Creative Commons Attribution 4.0 International License. Authors at Science Repository retain copyright to their work and allow others to copy, distribute, transmit, and adapt their work, provided proper attribution is given. Electronic edition: online edition: ISSN 2674-2489

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NLM ID: 101769245

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Recent Published Articles

Comparison of Lp-PLA2 Activity, Lp-PLA2 Mass and Lp-PLA2 mRNA in Acute Coronary Syndrome Patients

The Risk of Infective Endocarditis among COVID-19 Patients with Non-Medical Opioid Use

Modulatory Effects of L-Arginine on Methylxanthine-Induced Cardiotoxicity in Rats: A Differential Role for Nitric Oxide (NO)

Application of Cell Culture Models in Studying Viral Diseases (SARS, H1N1 Flu, MERS, COVID-19): A Review

In Press Volume 4, Issue 3

Opt-in Electrocardiogram Screening at High-School Physicals Does Not Identify Those at Highest Risk for Sudden Cardiac Death

Impact of Gender on Clinical Characteristic, Treatment and Outcome in ST Elevation Myocardial Infarction: A Hospital Based Study from North-Eastern India

How to Evaluate the Pulmonary Valve and Right Ventricular Outflow Tract in Prone Position during Invasive Mechanical Ventilation

Application of Cell Culture Models in Studying Viral Diseases (SARS, H1N1 Flu, MERS, COVID-19): A Review

Modulatory Effects of L-Arginine on Methylxanthine-Induced Cardiotoxicity in Rats: A Differential Role for Nitric Oxide (NO)

The Risk of Infective Endocarditis among COVID-19 Patients with Non-Medical Opioid Use

Comparison of Lp-PLA2 Activity, Lp-PLA2 Mass and Lp-PLA2 mRNA in Acute Coronary Syndrome Patients

Editorial Board

Palanisamy Sivanandy

Palanisamy Sivanandy Science Repository Editorial Board


Pharmacy Practice

International Medical University, Malaysia



Dr. Palanisamy Sivanandy is an eminent academician and researcher, has more than 10 years of teaching and research experiences. He has more than 20 years of experience in the pharmacy field. He has started his career as a dispensing pharmacist in the year 1997 as a Diploma Pharmacist; in 2005 he has completed his Pharmacy Undergraduation (B.Pharm.) from the Madurai Medical College, Tamil Nadu; in 2007 he obtained his Post Graduation (M.Pharm.) in Pharmacy Practice from Sri Ramkrishna Institute of Paramedical Sciences, Coimbatore, Tamil Nadu. He has completed his Ph.D. in the year 2013 from the prestigious Tamil Nadu Dr. MGR Medical University, Chennai and Good Clinical Practice Licensure Exam from Ministry of Health (MoH), Malaysia in 2014.

Keji Chen

Keji Chen Science Repository Editorial Board


President of the China Association of Integrative Medicine



Professor Keji Chen, MD., a World-renowned scholar, one of the most prominent pioneers of integrative East-West medicine in China. Academician of the China Academy of Science, Honorary President of the China Association of Integrative Medicine and the China Society of Genontology, President of the Expert Committee of World Federation of Chinese Medicine Societies. Professor Chen has served as the Consultant of WHO since 1979. He is Life-time Professor of Medicine to China Academy of Chinese Medical Sciences. He has invited as the Strategic Advisor of Scientific Innovation by Ministry of Public Health of China since 2016.

Professor Chen is one of the chief researchers of the studies on “Coronary Heart No.II” and the first clinical applier of Ligustrazine (one of the alkaloids of Radix Ligustracum Wallichii) in treating acute ischemic stroke and studies its metabolism for anti-platelet and anti-thromboxane production. He first carried out the studies for preventing restenosis after PCI by applying Chinese herbal formulas and got certain progress. He has systematized over 30,000 original medical archives of the Qing Royal Palace. In 2003, Professor Chen awarded the first prize in National Scientific Achievement in China, and has won ten more awards of World/National/Ministerial levels.

Martín Ricardo Arceluz

Martín Ricardo Arceluz Science Repository Editorial Board

Postdoctoral Researcher

Electrophysiology Department

University of Pennsylvania

United States

About Me

I went to medical school in Argentina (UNR) where I got my medical degree and I did my Cardiology residency in Argentina (Santa Fe) as well. The last year of my Cardiology residency, I did a rotation in the Arrythmia and Robotic Electrophysiology Unit in La Paz University Hospital, Madrid, Spain, one of the largest of the country. The following year, I applied and was awarded a European Heart Rhythm Association clinical fellowship in Electrophysiology returning to La Paz University Hospital, Madrid, Spain. During my two-year fellowship at La Paz University Hospital, I acquired independent mastery in the use of contemporary 3D mapping systems (CARTO, NavX Ensite) as well as latest balloon ablation strategies (Laser balloon). Under the guidance of my expert supervisor, Prof. Jose Luis Merino, President-elect of EHRA, I learned to independently perform a high number of transseptal punctures, 3D electro-anatomical mapping, and finally complex ablation including; atrial fibrillation, left atrial tachycardias, SVT, atrial flutter, and VT as second operator. In addition, I was actively involved in several clinical research projects, presenting our original results at national and international scientific meetings including the 2015 Young Investigators Awards Conference in Milan, Italy.


While completing my fellowship I also completed my Masters in Electrophysiology at CEU San Pablo University, Madrid, Spain under the direction of Prof. Jesus Almendral. Once I finished my EP clinical fellowship at La Paz University Hospital, I started a new EP clinical fellowship with a focus on clinical research with Dr. Jesus Almendral as my mentor at Monteprincipe University Hospital which led to defending my doctorate thesis “Additional New Entrainment Criteria for Macroreentrant Atrial Tachycardias” at CEU San Pablo University, Madrid, Spain in January 2020. Throughout this fellowship, I attended multiple conferences and courses and was a Young Investigator Award Finalist in the 2018 EHRA congress in Barcelona, Spain.


As I entered the final stage of my PhD, I decided to move from Madrid, Spain to Philadelphia, Pennsylvania to complete a research fellowship in the Electrophysiology department at the Hospital of the University of Pennsylvania. Currently I am finishing my Postdoctoral Electrophysiology Research Fellowship at the University of Pennsylvania (UPENN). On October 2021, I am starting a new position at UPENN as a researcher associate.

Honors & Awards

       i.          2006: Student Research Grant, National University of Rosario/Litoral, Argentina

     ii.          2007: Assistant Professor Grant, National University of Rosario/Litoral, Argentina

    iii.          2008: Faculty Nominated Commencement Speaker, National University of Rosario/Litoral, Argentina

    iv.          2014: EHRA Clinical Electrophysiology Fellowship Award

      v.          2018: EHRA Young Investigators Award finalist

    vi.          2015: EHRA Young Investigator Award (Oral presentation)

Robert J Chilton


Department of Medicine, San Antonio

University of Texas Health Science Center

United States


Robert J. Chilton, D.O., is an Associate Professor of Medicine and Director of the Cardiac Catheterization Laboratory at the Audie Murphy VA/University of Texas Health Science Center at San Antonio. A fellow of the American College of Cardiology, American College of Physicians, American College of Osteopathic Internists, and American Heart Association, Dr. Chilton also chairs the Electrophysiology Board Examination for the American Osteopathic Association and presides over the San Antonio chapters of both the Cardiovascular Society and American Heart Association. Dr. Chilton received his Bachelor of Science degree from Philips University, Enid, Oklahoma, and his D.O. from the University of Osteopathic Medicine and Surgery, Des Moines, Iowa. He completed his internship at Wright-Patterson Air Force Base, Dayton, Ohio; his residency at the University of Oklahoma Health Science Center, Oklahoma City, Oklahoma; and a cardiology fellowship at the Wilford Hall United States Air Force Medical Center, San Antonio, Texas. Dr. Chilton is board certified in internal medicine, cardiovascular disease, and electrophysiology. Over the past 20 years, Dr. Chilton has authored numerous articles, book chapters, abstracts, and presentations on cardiology. He has developed educational materials and has lectured widely, garnering several awards for his academic contributions, including 1994 Outstanding Teacher from the University of Texas Health Science Center at San Antonio.

Nicola Maurea

Chief, Division of Cardiology

Istituto Nazionale Tumori IRCCS



Nicola Maurea is graduated in Medicine and he is specialized in Cardiology and Internal Medicine; he obtained all degrees with full marks and honors from University of Naples Federico II. He is the Director of Division of Cardiology of National Cancer Institute, Pascale Foundation, Naples. He is a distinguished expert in the field of Cardioncology and he is the President of Italian Association of Cardioncology. Moreover, he is Fellow of the American College of Cardiology and Fellow of the European Society of Cardiology. He is author of many papers in international peer reviewed journals and many abstracts presented at international meetings of cardiological and oncological societies and he has been invited speaker many times at international and national conferences.

Francesco Vetta

Francesco Vetta Science Repository Editorial Board

Director U.O.Cardiology

Cardiology Department

Saint Camillus International University of Health Sciences, Rome Italy



Francesco Vetta is currently working as director of the Center for Arrhythmology and Electrophysiology of Paideia Hospital in Rome. Prof. Vetta has graduated in Medicine and Surgery with honors, in 1991, at the University of Studies of Rome "La Sapienza". Subsequently, at the same University, he obtained a specialization in Geriatrics, and in 2004, he specialized in Cardiology at the University of Rome "Tor Vergata". During his professional training he also attended a II level Master's in "Electrophysiology and cardiac electrostimulation", at the Catholic University of Rome, a 1st level Master in "Cardiology for images", at the University of Rome " La Sapienza", and a specialization course in "Arterial hypertension" at the University of Pisa. Since 2013 he has been Director of the Cardiology Unit at the Israelite Hospital in Rome, where he also directs the Center for Arrhythmology, Electrophysiology and Cardiac Electrostimulation. It deals in fact with clinical cardiology, arrhythmology and cardiac electrostimulation, having carried out as first operator about 5000 PMK implants, including biventricular and over 600 defibrillators. Previously he was Deputy Chief of the Cardiology Unit of the "SS Gonfalone di Monterotondo" Hospital where he was initially Head of the Center for the study and therapy of arterial hypertension, then Responsible for the study of Sincope and finally Head of UOS of Arrhythmology and cardiac electrostimulation. Prof. Francesco Vetta has focused in particular on studies concerning cardiovascular and arrhythmological diseases, especially in geriatric age, with participation in numerous national and international courses and conferences, which has allowed a scientific production quantifiable in about 160 publications in national and international journals, as well as chapters of scientific books and guidelines. He has participated as a speaker at numerous national and international congresses. President of the National Congress of Cardiogeriatry held annually since 2003.

Edimar Alcides Bocchi

Edimar Alcides Bocchi Science Repository Editorial Board

Associate Professor

Cardiopulmonary Department

São University Medical School



Edimar Alcides Bocchi, M.D., Ph.D., trained as a cardiologist at the Heart Institute (InCor) Of São Paulo University Medical School and obtained his Ph.D. at the São Paulo University Medical School. Currently, he serves as the head of heart failure clinics at Heart Institute (Incor) of Hospital das Clinicas of São Paulo University Medical School, associate professor of São University Medical School, and director of the heart failure team at the Heart Institute (InCor) of São Paulo University Medical School. His areas of clinical and research interest include heart failure, Chagas heart disease, cardio-oncology, and exercise in heart failure. Dr. Bocchi has amassed 276 publications in peer-reviewed journals, contributed to 63 book chapters, and serves as the national coordinator for several randomized clinical trials, including the BELIEF, COMMANDER, SHIFT, RAD 2401, CECCY, and Remadhe trials.

Mohammed Idhrees

Mohammed Idhrees Science Repository Editorial Board


Dept. Of Cardiac Surgery

Institute of Cardiac and Aortic Disorders



Dr. Mohammed Idhrees is a Senior Resident in the Department of Cardiovascular and Thoracic Surgery at Sree Chitra Thirunal Institute for Medical sciences and Technology located at Thiruvananthapuram, Kerala, India.



Department of Cardiology

Grant Medical College & J.J. Group of Hospital, Mumbai



Dr. Lekha Pathak is the Director and Head of the Cardiology Department at Nanavati Super Speciality Hospital, Mumbai, India. She has an experience of 46 years. She completed M.B.B.S. from Netaji Subhash Chandra Bose Medical College, Jabalpur in 1965, D.M. - Cardiology from King Edward Memorial Hospital and Seth Gordhandas Sunderdas Medical College in 1971 and M.D. - General Medicine from Netaji Subhash Chandra Bose Medical College, Jabalpur in 1968. She has done over 10000 Interventional procedures for past 10 years. Dr. Lekha Pathak has been awarded with Lifetime achievement award by Ex. President APJ Abdul Kalam for outstanding contribution in the field of Cardiology 2008, Priyadarshani award 2008, Doctor of Science (D.Sc.) by University of Loyola, Chicago, USA 2012 and many more. She is a member of Maharashtra University of Health Sciences, Padmashree Dr. D Y Patil University - Member Management Council, Association of Physicians of India (API) and Indian College of physician. Some of the services provided by the doctor are: Carotid Angioplasty and Stenting, Coronary and Non-Coronary Interventions, Angioplasty and Stenting, Interventional procedures and Minimally Invasive Cardiac Surgery.

Kai-Sheng Hsieh

Kai-Sheng Hsieh Science Repository Editorial Board


Pediatrics Department

Shuanghe Hospital, Taipei Medical University

Taiwan, Province of China


Dr. Hsieh is one of the pioneers in Pediatric Echocardiography. He underwent clinical fellow training in Pediatric Cardiology at Boson Children’s Hospital, Harvard Medical School in 1982-1984. After returning to Taiwan, he has been actively participated in various academic activities in Pediatric Cardiology and Pediatric Critical Care. He has been elected as the executive board members in the Society of Ultrasound in Medicine, Republic of China for multiple times during the past 30 years. He is now the executive board member of Asian Pacific Society of Echocardiography. He has been the 2nd President of Taiwan Society of Critical Care Medicine (TSCCM 2001-2004) and he founded the Taiwan Society of Pediatric and Intensive Critical Care and Intensive Care Medicine (TSPICCM) in 2016. He has published about 250 peer-reviewed scientific papers and 10 Book Chapters.

Rabindra Nath Das

Rabindra Nath Das Science Repository Editorial Board


Department of Statistics

The University of Burdwan



Rabindra Nath Das is a Professor in the Department of Statistics, The University of Burdwan, Burdwan, West Bengal, India. He holds a Ph.D., in Statistics, from The University of Burdwan, India, and Post-Doc from Seoul National University, Seoul, Korea. He has authored more than 125 research articles, and along with a research Monograph entitled- Robust Response Surfaces, Regression, and Positive Data Analyses, published from CRC Press, Taylor & Francis, Chapman & Hall. He wrote research articles on Design of experiments, Regression Analysis, Demography, Quality Engineering, Civil Engineering, Epidemiology, Medical sciences, Environmental, Natural sciences, History etc. His special area of interest is on Design of experiments, Regression analysis, Quality Engineering and Epidemiology. He has received ‘Gopal Kanji Prize 2009’ by The Journal of Applied Statistics and Routledge publications’ for the best article published in volume 36(7), pp. 755-767. He has received certificate of appreciation for outstanding research by the Editor-In-Chief, Journal of Thyroid Science, given in the Journal Website, for the paper- Vol. 6, No. 2, pp. 1-15. He is acting as Editor, Associate Editor, Executive Editor, Editorial Board Member of more than 135 Journals in Statistics, Physical Sciences, Medical Sciences. He has acted as a Research Professor in 2018-2019 (for six months) and 2019 (for three months) in Data Science for Knowledge Creation Research Center, Statistics Department, Seoul National University, South Korea.

Honors & Awards

       i.          Editors, Associate Editors, Editorial Board Members: More than 132 Journals.

     ii.          Manuscript reviewer of many Statistics, Epidemiology, Medical Sciences Journals.

    iii.          2015: Appointed as a Reviewer, Mathematical Reviews.

    iv.          2011: Certificate of Appreciation for outstanding Research by Editor-In-Chief, Journal Thyroid Science, given in the Journal Website (for the paper {Das, R.N. (2011). \The Role of Iodine in the Thyroid Status of Mothers and Their Neonates," Thyroid Science, Vol. 6, No. 2, pp. 1-15.).

      v.          2009: `Gopal Kanji Prize 2009' by The Journal of Applied Statistics and Routledge Publications for our article published in Volume 36, No. 7, pp. 755-767 (Das, R.N. and Park, S.H. (2009). `A measure of robust slope-rotatability for second-order response surface experimental designs').


    vi.          2006-07: Post-Doc Research Fellowship, Seoul National University, BK-21, Republic of Korea.

  vii.          1991: Junior Research Fellowship, Council of Science and Industrial Research, Govt. of India.

 viii.          1990-1991: Junior Research Fellowship, West Bengal State Govt., India.

    ix.          1985: National Scholarship, Govt. of India.

      x.          1980: National Scholarship, Govt. of India.

    xi.          2006-2007: Principal Investigator, entitled Regression analysis with correlated errors and its applications in block designs, The University of Burdwan, Burdwan, W.B., India, Minor Research Project, UGC, Govt. of India, Rs. 45,000.

2002-2003: Principal Investigator, entitled- Robust Rotatable Designs and its Applications in Reliability Theory, The University of Burdwan, Burdwan, W.B., India, Minor Research Project, UGC, through The University of Burdwan, Rs. 11,000.

Giuseppe Lanza

Giuseppe Lanza Science Repository Editorial Board

Senior Academic Researcher, Assistant Professor

Department of General Surgery and Medical-Surgical Specialties

University of Catania



I was born in Catania (Italy) in 1982. I currently work as a Senior Academic Researcher and Assistant Professor at the University of Catania (Italy). After graduation with honours in Medicine, I trained at the School of Neurology and got the international PhD at the same University. As visiting Clinical Research Fellow, I further trained at the Department of Neuroscience and Clinical Neurophysiology of the Newcastle University (UK). In 2013 I was selected for a Scientific Fellowship promoted by the European Federation of Neurological Societies (EFNS). From 2013 to October 2018, I worked as a Consultant Neurologist at the “Oasi Research Institute–IRCCS” in Troina (Italy), which is a Collaborating Center of the World Health Organization (WHO). From 2015 to October 2018, I taught Neurology at the University of Enna (Italy). I have authored more than 130 publications in internationally-indexed peer-reviewed Journals and Conferences or Meetings, and I currently serve as Editor and invited Reviewer of several international Journals. More recently, I have obtained the Master of Science in Clinical Research and the National Scientific Qualification as Full Professor (procedure for the Italian University Professor recruiting, based on rigorous criteria of scientific qualification).

Uwe Nixdorff

Uwe Nixdorff Science Repository Editorial Board

Associate Professor, Medical CEO, External Faculty Member, Internist


Hanako GmbH, Friedrich-Alexander University, European Prevention Center


Dmitrii Ognerubov

Dmitrii Ognerubov Science Repository Editorial Board


National Medical Research Center of Cardiology, Moscow

Russian Federation

Fares El-Sayed Mohammed Ali

Fares El-Sayed Mohammed Ali Science Repository Editorial Board

Faculty member

Assistant professor of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch

Al-Azhar University


Barbara Iyen

Barbara Iyen Science Repository Editorial Board

Clinical Assistant Professor

Primary Care

University of Nottingham

United Kingdom


HONG S. LU Science Repository Editorial Board

Technical Review Editor

Saha Cardiovascular Research Center and Physiology

University of Kentucky

United States

Sven Kaese

Sven Kaese Science Repository Editorial Board

Consultant/attending physician and senior lecturer

Department of Cardiology and Critical Care Medicine

Johannes Wesling University Hospital, Ruhr University Bochum


Shanti Narsibhai Patel

Shanti Narsibhai Patel Science Repository Editorial Board

Internal Medicine Resident

Maimonides Medical Center

United States

Peysh A Patel

Peysh A Patel Science Repository Editorial Board

Cardiology Registrar

University of Leeds

United Kingdom

Salvatore Mancarella

Associate Professor


University of Tennessee Health Science Center

United States

Kaizheng Gong


Department of Cardiology

Yangzhou University


Ran Wang

Associate Professor

Department of Respiratory Medicine and Critical Care Medicine

The First Affiliated Hospital of Anhui Medical University


Mojtaba Parvizi

Assistant Professor of Medicine

Division of Endocrinology, Diabetes, Nutrition

Mayo Clinic, Rochester, Minnesota

United States

Maria Camila Pruper de Freitas

Maria Camila Pruper de Freitas Science Repository Editorial Board

Researcher Nutritionist

Nutrition Department

Faculty of Public Health



Ph.D. (2019) and Master of Science (2015) by the Nutrition Program in Public Health, Faculty of Public Health, University of São Paulo (FSP-USP). Graduated in Nutrition (2012) from Universidade Nove de Julho. Experience in scientific research with an emphasis on lipid metabolism, nutrition biochemistry, cardiovascular diseases, biostatistics and data analysis. The projects in which she participate evaluate the effects of nutritional components on lipid, oxidative, inflammatory and immunological parameters related to atherosclerosis, obesity and chronic non-communicable diseases, with a focus on cardiovascular diseases, biostatistics and analysis of research data.

Ederson Laurindo Holanda de Sousa

Ederson Laurindo Holanda de Sousa Science Repository Editorial Board


Department of clinical and toxicological analysis

Federal University of Ceara - Brazil



Master in the Medical Surgery program at the Federal University of Ceará - UFC, with an emphasis on Molecular Biology. Graduated in Pharmacy from UFC and in Chemical Processes from Instituto Federal do Ceará. He is currently a laboratory technician - Pharmacotechnics at the Federal University of Ceará. Has experience in Pharmacy, with emphasis on Pharmacotechnics; Quality Control of Medicines and Cosmetics; Analytical Chemistry and Clinical Pharmacy.

Michael Hughes

Michael Hughes Science Repository Editorial Board


Institute of Inflammation and Ageing

University of Birmingham

United Kingdom

Marcela Antonini

Marcela Antonini Science Repository Editorial Board

PhD student

University of São Paulo


Yuekun Lang

Research Affiliate

Wadsworth center, New York department of health

Health Research, Inc.



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For submission authors can directly submit manuscript to

Manuscripts number will be provided to the corresponding author within 72 hours for the respective manuscript submitted.

  • 14 day review process with international peer-review standards
  • Timeline of processing from Submission to Publication is 30 days
  • Manuscript will be published within 7 days of acceptance

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