Luteinizing Hormone and Ovarian Stimulation for In-Vitro Fertilization: Do Science and Business Always Agree?

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The manuscript discussed the product composition of human menopausal gonadotropin, GnRH analogues, GnRH antagonists and recombinant LH. Further, the commentary described population-based randomized controlled trial (RCT)’s and patients who can benefit from LH supplementation. Product development often results in financial and practical considerations, resulting in deviating from physiology. Lastly, the authors suggest that there is a need to revisit physiology and clinical thinking to individualize the treatment strategy as per the requirement of the “every-day” patients.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: The manuscript gives a commentary on luteinizing hormone and ovarian stimulation for in-vitro fertilization. The paper mainly highlighted the association between business decisions and scientific development, followed by the major steps in the development of fertility medications. Further, the authors suggested that population-based studies may be replaced with studies on specific endocrine events that may expose the individual patient to transient LH deficiency and also illustrate the need for LH supplementation.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team