Pulmonary Thrombosis in Acute Respiratory Distress Syndrome: Theory, Evidence, and Clinical Relevance to Resource-Limited Settings

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for

researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them coherent?

A: Very good

Comments:

This review article synthesizes the current treatment options of pulmonary thrombosis in acute respiratory distress syndrome and proposes why in resource-limited settings screening limitations will affect early intervention. The review is well supported with briefly explained figure and tables. Based on the data obtained from relevant literature, the study concludes that there is strong link between thrombosis and acute respiratory distress syndrome (ARDS) due to the dual activation of the two pathways involved. The review aptly recommends focus to be placed on the prevention, early recognition, and treatment of pulmonary thrombosis as part of endotheliopathy-associated vascular microthrombotic disease.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: The aim of this review article is to specifically highlight the pathophysiology of acute respiratory distress syndrome (ARDS) and how it links to pulmonary thrombosis. This study holds significance as pulmonary thrombosis is a serious issue and a topic highly relevant given the current coronavirus pandemic situation which makes this link furthermore critical. This article adequately reviews the current treatment options, underlining that potentially life-saving thrombosis-screening procedures could be lacking in resource-limited settings.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team