Surgical Management of Locally Advanced Breast Cancer: Recommendations of the Brazilian Society of Surgical Oncology

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments: The manuscript discusses the pathological conditions, the response to therapy, and the risk for necrosis which must be considered in relation to the surgical indication for locally advanced breast carcinoma (LABC). The author suggests multidisciplinary team in evaluating the pros and cons of the surgical aspects and discussing the same with the patients.

Literature

Q: Does the author utilize relevant literature?

A: Very Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good

Writing style

Q: Is it clear and understandable?

A: Good

Comments: There are few issue found in the manuscript, which are as follows:

·       In 1^st paragraph, 5^th sentence is rewritten as “The group pointed conditions related to this condition as the basis of the recommendations”.

·       In 3^rd paragraph, 4^th sentence, “but it is usually studied separately because its biological behavior is more severe” is reframed as “but it is usually studied separately due to its more severe biological behaviour”.

·       Under Myocutaneous flaps, 6^th paragraph, 2^nd sentence, “although its necessary more studies … necrosis rate by author” is reframed as “although more studies are necessary to increase the global casuistry; all the studies were retrospectively carried out and a great variability was observed in relation to the necrosis rate by author”.

Further comments on the paper

Comments: The manuscript provides various surgical aspects on locally advanced breast carcinoma (LABC) which is proposed by Brazilian Society of Oncological Surgery. It comes up with a review on different surgical techniques and complications associated with thoracoabdominal or myocutaneous flaps. Further, it provides relevant literature on the clinical aspects, the tumor conditions, response to neoadjuvant therapy, choice of flaps and tumor biology. The article also illustrates in detail the resectability, patchwork conditions in LABC patients. The author provides relevant recommendations on the diagnosis, surgical approaches and treatment associated with LABC. Lastly, it puts forth the different perspectives related to the understanding and management of the disease and its complications through various surgical techniques.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team