Intraoperative Thrombolysis for Pulmonary Embolism during Thymoma Resection

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Very good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Very good

Comments:

This case report demonstrates the value of clinical reasoning under stressful conditions, when situations requiring opposing treatments co-exist, such as haemorrhage and thromboembolism. The case description is adequate. The Discussion explains the challenges in treating the patient in the present case clearly. It also offers useful suggestions with respect to the treatment regimen. In this case poor windows prevented a proper transthoracic echocardiogram (TTE) and a transoesophageal echocardiography (TOE) could not be performed. The study aptly summarizes that during such circumstances multidisciplinary teamwork is of paramount importance for the individualization of treatment.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Not Applicable.

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This case report of a 48-year-old male patient presents a complex case of a thymoma resection leading to pulmonary embolism (PE) requiring intraoperative thrombolysis and to postoperative blindness, possibly in the setting of superior vena cava syndrome (SVCS). There are only a few reported cases in the literature of suspected intraoperative PE, without echocardiographic or angiographic confirmation, treated solely with thrombolysis. This case study holds significance as it demonstrates that, when facing an imminent disaster, a risky decision not necessarily conforming to current practice but based on individualization of treatment can be life-saving.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team