Clinical Case of Castleman’s Disease Located at the Mesorectum

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Comments:

The subheading “Introduction” has been introduced within Abstract.

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Very good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

Comments:

The Discussion explains the challenges in treating the patient in the present case clearly. It also offers useful suggestions with respect to the treatment regimen. In the present case, the morphological characteristics testified in favor of the most frequent variant of Castleman's disease - the hyaline-vascular local type, with the manifestation of pain syndrome. The Conclusion section comments on the rarity of the condition and states that Castleman's disease should be considered as a differential diagnosis of neoplasms of mesorectal fat.

Literature

Q: Does the author utilize relevant literature?

A: Good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This study reports the case of Castleman’s disease in the mesorectum of a 48-year-old man, who complained of lumbar pain. Castleman’s disease is most commonly presented as a solitary mass in the mediastinum, although sometimes with sites at the neck, axilla, mesentery, pancreas, pelvis and retroperitoneum. The study holds significance as only few cases of this disease with localization in pararectal lymphatic tissue have been described as clinical cases in the literature.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team