Aberrations of TBX2-CHK2-p53 Signaling Pathway and its Role in Malignant Peripheral Nerve Sheath Tumors

Review Data

Purpose and Significance of Study: This study was conducted on the genetic aberrations in the TBX2-CHK2-p53 pathway and concluded that TBX2 and CHK2 might be useful markers for malignant peripheral nerve sheath tumors.

Fit with Scope of Journal: The manuscript is of very high interest for the Journal of Surgical Oncology.

 

o   The manuscript contains a few errors (already corrected in the galley proof, except the highlighted ones, which require the author’s attention), which are listed below –

 

The common errors are –

·       In the Abstract, omission of the full forms of various abbreviations, e.g., MPNST, NGS, IHC, AJCC, DFS and OS.

·       In a couple of places, “et al” was used in place of “etc.”, e.g., in the 1st and 5th sentences of point 3.1.

·       Omission of articles in many places throughout, e.g., before “TBX2-CHK2-p53 pathway” in many places.

 

In the Abstract –

  Under Results –

·       In the 3rd sentence, “that” must be inserted after “found”.

·       In the 3^rd and 4^th sentences, “positive” must be replaced with “positively”.

In the Materials and Methods –

  Under point 2.1 –

  In the last paragraph –

·       In the last sentence, “No.7 patient” must be replaced with “patient no. 7”.

  Under point 2.3  –

·       In the heading, “the” must be removed.

  Under point 2.5  –

·       In the 2nd sentence, “proteins” must be replaced with “protein”, and “were” must be replaced with “was”.

·       In the 3rd sentence, “is” must be replaced with “was”.

·       In the last sentence, “were” must be replaced with “was”.

In the Results –

  Under point 3.1 –

·       In the 5th sentence, “cancer related” must be hyphenated.

  Under point 3.2 –

  In the 1st paragraph –

·       In the 1st sentence, “outcome” must be replaced with “outcomes”.

  In the 2nd paragraph –

·       In the 3rd sentence, “frame shift” must be written as a single word.

  Under point 3.4 –

  In the 2nd paragraph –

·       In the 2nd sentence, “disease free” must be hyphenated.

  Under point 3.5 –

  In the 1st paragraph –

·       In the 2nd sentence, “a” before “NF1” must be replaced with “an”.

In the Discussion –

  In the 2nd paragraph –

·       In the 2nd sentence, “what’s more” must be replaced with “moreover”, and “the” must be removed.

·       In the 3rd sentence, “relationship” must be replaced with “relationships”, and “still need further studied” must be replaced with “need further study”.

  In the last paragraph –

·       In the 3rd sentence, “cells” must be replaced with “cell”.

Author Info

Chao Zhang Fangyuan Chang Hongji Dai Jilong Yang Ting Li Xiaoling Du

Corresponding Author

Jilong Yang
Departments of Bone and Soft Tissue Tumor, Tianjin Medical University Cancer Institute and Hospital, Tianjin, P.R. China

Article Info

Article Type

Research Article

Publication history

Received: Fri 10, Apr 2020
Accepted: Mon 27, Apr 2020
Published: Wed 29, Apr 2020

Copyright

© 2023 Jilong Yang. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2020.02.09