Dedifferentiated Chondrosarcoma with Epithelial Differentiation: A Case Report and Review of the Literature

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Author Info

Humaid Al Farii Marc-Antoine Ricard Motaz AlAqeel Robert Turcotte Sungmi Jung

Corresponding Author

Humaid Al Farii
Department of Orthopaedic Oncology, Division of Orthopaedic Surgery, McGill University, Montreal, Canada

A B S T R A C T

Case: We describe a case of 72-year-old male with dedifferentiated chondrosarcoma with osteosarcomatous and epithelioid (squamous) dedifferentiation. As first described in the literature by Dahlin and Beabout, a well-differentiated benign chondral lesion abruptly juxtaposed to a high-grade non-cartilaginous component is the classical definition of a chondrosarcoma [1]. The non-cartilaginous component is typically an osteosarcoma, fibrosarcoma or malignant fibrous histiocytoma with rare instances of leiomyosarcoma, giant cell tumor and rhabdomyosarcoma [2]. Conclusion: We report our rare instance of squamous dedifferentiation of a dedifferentiated chondrosarcoma along with other five cases that have been reported so far in the literature

Article Info

Article Type

Case Report and Review of the Literature

Publication history

Received: Tue 07, Apr 2020
Accepted: Tue 21, Apr 2020
Published: Mon 27, Apr 2020

Copyright

© 2023 Humaid Al Farii. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2020.02.08