Biomechanical Study of Simulated Metastatic Peri-Acetabular Defects

Author Info

Francis R. Patterson Jennifer Thomson Joseph Benevenia Kathleen S. Beebe Michael N. Kang

Corresponding Author

Jennifer Thomson
Rutgers New Jersey Medical School Department of Orthopaedics, NJ

A B S T R A C T

Peri-acetabular metastasis presents the risk of fracture. However, the relationship between bone loss and fracture risk is unknown. Utilizing fresh frozen intact cadaver pelves, Harrington class I lesions were simulated. Lesions were categorized as small (<40%) or large (>40%) Axial loading was applied in a quasistatic mechanism by a mechanical testing system to catastrophic failure, with the load-to-failure force being measured. There was statistical difference in the load-to-failure force between hemi-pelves with large defects and their matched controls. It was found that mean load-to-failure strength of a hemi-pelvis with a Class I defect was more than 2.3-2.45 times the calculated hip joint reactive force. Thus, it was concluded that a pelvis with a peri-acetabular defect of greater than 40% has a significantly lower load-to-failure strength compared to an intact pelvis. However, even this large Class I defect will fracture only at supraphysiologic loads and the hip joint may not normally be exposed to forces that high.

Article Info

Article Type

Research Article

Publication history

Received: Tue 16, Oct 2018
Accepted: Mon 05, Nov 2018
Published: Sat 29, Dec 2018

Copyright

© 2023 Jennifer Thomson. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JSO.2018.01.003