Small Cell Carcinoma of the Breast: A Report of 2 Cases and Literature Review

Small Cell Carcinoma of the Breast: A Report of 2 Cases and Literature Review

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for


A: Very good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Excellent



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good


Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Very good



The case descriptions are adequate. The Discussion section discusses current literature regarding diagnosis, treatment, and prognosis in small cell carcinoma of the breast. Extrapulmonary small cell cancers are rare, and treatment regimens have generally followed lung treatment plans. The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. It also offers useful suggestions with respect to the treatment regimen. The report aptly recommends collection of information about these rare tumors for guiding treatment in the future.



Q: Does the author utilize relevant literature?

A: Very good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good


Writing style

Q: Is it clear and understandable?

A: Very good


Further comments on the paper

Comments: This case report presents two cases of triple-negative small cell carcinoma of the breast. This study holds significance as primary small cell carcinoma of the breast is rare and the majority of the medical literature about breast small cell carcinoma is individual case reports. Both the patients in the study responded to neoadjuvant cisplatin/etoposide, although the patient in case two did not have a lasting response.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Science Repository Team


Author Info

Corresponding Author
Paige Aiello
Department of Surgery, Wayne State University School of Medicine, Detroit, Michigan, USA

Article Info

Article Type
Case Report and Review of the Literature
Publication history
Received: Mon 13, Jun 2022
Accepted: Wed 29, Jun 2022
Published: Tue 12, Jul 2022
© 2021 Paige Aiello. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2022.07.02