Gastric Epithelioid Haemangioendothelioma: A Case Report

Gastric Epithelioid Haemangioendothelioma: A Case Report

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for


A: Good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good

Comments: The Objective subheading should precede the Introduction subheading.



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very Good


Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good


Comments: The Discussion establishes that epithelioid haemangioendothelioma (EHE) is a rare vascular neoplasm. The Discussion illustrates the clinical presentation of EHE. Diagnosis by endoscopy and biopsy is often difficult and unsatisfactory due to the submucosal location of the tumor. Ultrasound or computed tomography may be useful for accurate preoperative staging. The Discussion highlights that histopathological examination supported by immunohistochemical findings is important for the accurate diagnosis of EHE. Based on the data obtained from relevant literature, the study concludes that surgery in the form of wide excision should be the treatment of choice. The study recommends detailed clinical evaluations and a complete follow-up of the patient due to the borderline biological behaviour of this neoplasm.



Q: Does the author utilize relevant literature?

A: Very Good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good


Writing style

Q: Is it clear and understandable?

A: Good

Further comments on the paper

Comments: This case report presents the case of a 58-year-old white woman suffering from chronic iron-deficiency anaemia and had positive faecal occult blood test, with a medical history of well-compensated celiac disease. The tumor showed the histological and immunohistochemical characteristics of the epithelioid haemangioendothelioma (EHE). EHE is a vascular neoplasm, with a very low incidence of occurrence. The study illustrates the rarity of this tumor and the difficulties in diagnosing it preoperatively in many cases. After a surgical resection of the tumor the patient did not develop any postoperative complications and was discharged one week after the surgery. In a follow-up six months later, no recurrence was observed. The study concludes that surgery in the form of wide excision should be the treatment of choice for this rare neoplasm.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team


Author Info

Corresponding Author
Mitri Roberto
Gastroenterology and Endoscopy Unit, ARNAS Civico-Di Cristina-Benfratelli Hospital, Palermo, Italy

Article Info

Article Type
Case Report
Publication history
Received: Mon 12, Apr 2021
Accepted: Wed 05, May 2021
Published: Wed 19, May 2021
© 2021 Mitri Roberto. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.SCR.2021.05.02