Multiple Synchronous Squamous Cell Cancers of the Skin and Esophagus: Differential Management of Primary Versus Secondary Tumor

Multiple Synchronous Squamous Cell Cancers of the Skin and Esophagus: Differential Management of Primary Versus Secondary Tumor

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for


A: Good


Comments: The word “differentiate” in the title has been changed to “differential”.


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good


Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good


Comments: The Discussion gives a brief account of literature stating esophageal cancer as the eighth most common type of cancer worldwide. This further highlights the late diagnosis of the disease as the cause of high mortality rate. It clearly illustrates the use of 18F-FDG-PET during the diagnosis of patients with squamous cell esophageal cancer (SCEC). The report concludes by stating that the recent diagnostic techniques and the increased survival of oncologic patients have made frequent presentations of the uncommon multiple primary tumors (MPT). Lastly, it suggests the multidisciplinary analysis of the disease, which can positively influence the quality of life and prognosis of MPT.



Q: Does the author utilize relevant literature?

A: Good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Not applicable.


Writing style

Q: Is it clear and understandable?

A: Good


Further comments on the paper

Comments: This report presents a 66-year-old female with mild dysphagia, which later revealed to a poorly differentiated squamous cell carcinoma (SCC). This case further describes the patient’s clinical case with double primary esophageal and cutaneous squamous cell carcinomas to establish the potential relationship between the carcinomas and define the appropriate diagnostic and therapeutic strategies for both primary tumors.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team 


Author Info

Corresponding Author
Didier Mutter
General, Digestive, and Endocrine Surgery Department, Nouvel Hôpital Civil, Université de Strasbourg, Strasbourg, France

Article Info

Article Type
Case Report
Publication history
Received: Mon 16, Nov 2020
Accepted: Tue 01, Dec 2020
Published: Tue 15, Dec 2020
© 2021 Didier Mutter . This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository. All rights reserved.
DOI: 10.31487/j.SCR.2020.12.11