Analysis of an End Neuroma 6 Months after Capping with a Bioresorbable Polycaprolactone Cap (NEUROCAP®) in a Human Model

Analysis of an End Neuroma 6 Months after Capping with a Bioresorbable Polycaprolactone Cap (NEUROCAP®) in a Human Model

Review Data

Aim of the study: To discover the status of an end neuroma through months after capping with a bioresorbable polycaprolactone cap called NEUROCAP®, this being the first such study in a human model.


This manuscript is of high interest to the journal Surgical Case Reports.

The manuscript discusses in detail the findings during multiple surgeries after capping an end neuroma in a 74-year-old man with a bioresorbable polycaprolactone cap (NEUROCAP®). The fact that this method of painful neuroma treatment is potentially pain-relieving unlike the innumerable ineffective methods available, and that this study is the first of its kind in a human model, makes the publication of the manuscript worthwhile. 

The information provided in the Conclusion section seems to be more fitting for the Introduction section. The Conclusion section must instead comprise some takeaways from the research findings.

There are many minor errors, which are listed below –

In the Abstract section – 

  • In the 4th sentence, the words “something has to be done” sound too informal; instead the words “additional measures need to be taken” are suggested. 
  • In the 5th & 8th sentences, using the word “ending” instead of “end” is suggested. 
  • “,” needs to be inserted at the following places – 
    • In the 5th sentence, after “nerve end” 
    • In the 6th sentence, after “thinner cone” 
    • In the 8th sentence, after “resorbs” 
  • In the last sentence, the word “study” needs to be inserted after “this”, and “,” needs to be inserted after “kind”. 

In the Introduction section – 

  • The words “in to” need to be replaced with “into” in the following places – 
    • In the 2nd sentence 
    • In the 6th sentence 
  • In the 6th sentence, “the” needs to be inserted before “retrograde”. 
  • In the 8th sentence, the word “suppressing” is spelled wrong. 
  • In the 9th sentence, “,” needs to be inserted after “date”. 

In the Methods section – 

  • In the 1st sentence, the word “polycaprolactone” must be written as a single word. 

In the Case Report section – 

  In the 1st paragraph – 

  • In the 2nd sentence, “,” must be inserted after “injury” and after “to the ring” 
  • In the 3rd sentence, “a” must be inserted before “precision pinch”. 
  • In the 4th sentence, “an” must be inserted before “excellent” 
  • In the 5th sentence, “but” must be inserted after “radial side pain,”. 

  In the 2nd paragraph – 

  • The 1st sentence must be broken after “territory”. 
  • In the 2nd sentence, the word “surgery” must be inserted after “this”. 

  In the 4th paragraph – 

  • In the 2nd sentence, “a” must be inserted before “precision grip” and “the” before “thumb” and “ring”; “,” must be inserted after “ring finger”. 

  In the 6th paragraph – 

  • In the 2nd sentence, the word “small” must be used in place of “poor”. 
  • In the 3rd sentence, the string of words “original index finger nerve stump neuromas” are confusing; so, they may be rearranged as “nerve stump neuromas of the original index finger”. 

  In the 7th paragraph – 

  • In the 2nd sentence, “the” must be inserted before “scar”. 
  • In the 3rd sentence, the words “of these” must be removed. 

  In the 8th paragraph – 

  • “,” must be inserted at the following places – 
    • In the 1st sentence, after “neuromas” 
    • In the 2nd sentence, after “operation” and after “cap” 

In the Histopathology section – 

  In the 1st paragraph – 

  • The 3rd sentence must be broken down after “appearance” and “,” inserted after “however”. 
  • In the 5th sentence, “this” must be replaced with what exactly it refers to; it is unclear. 

  In the 2nd paragraph – 

  • The 1st sentence must be reconstructed as its meaning is not clear. 
  • In the 2nd sentence, “,” must be inserted after “specimen” and “a” must be inserted before “patchy”; the meaning of the words “florid foreign body type giant cell reaction” is unclear; “spaced” must be replaced by “space”; “the” must be inserted before “degrading”; “)” at the end of the sentence must be removed. 
  • In the 3rd sentence, “short” must be replaced with “small”. 

  In the 4th paragraph – 

  • In the last sentence, “the” must be inserted before “section”. 

In the Discussion section – 

  • In the 2nd sentence, “I” on “in” at the start must be capitalized. 
  • In the 3rd sentence, “2” must be written as “two”. 
  • In the 4th sentence, “of these” after “both” may be removed. 
  • “,” must be inserted at the following places – 
    • In the 5th sentence, after “failures” and “half of these” 
    • In the 6th sentence, after “opening” 
    • In the 12th sentence, after “caps” 
    • In the 17th sentence, after “thicker” and “symptoms seen” 
    • In the 18th sentence, after “compact growth” 
    • In the 19th sentence, after “ideally”, after “nerve stump”, after “slide” and after “figure 4” 
  • The words “et al” must be followed by a “.” at the following places – 
    • In the 7th sentence 
    • In the 10th sentence 
  • In the 8th sentence, “then” before “finally” must be replaced with “and”. 
  • In the 12th sentence, the word “today” must be written as a single word. 
  • The 13th sentence is too long; so, it must be written like “…rat models. There, the weight ratio…” 
  • In the 17th sentence, “the” must be inserted before “expression”. 
  • In the 18th sentence, “This echoes our findings where” must be replaced with “These findings echo ours, where”. 
  • The 19th sentence is unnecessarily long; so, it must be broken at “nerve stump” and “cap would have been”, to make three sentences. 

In the Conclusion section – 

  • In the 1st sentence, “its” must be inserted before “aetiology” and “is” must be replaced by “are”. 
  • The 1st sentence is unnecessarily long; breaking the sentence after “poorly understood” is recommended. 
  • In the 2nd sentence, there must be “the” before “latest” and “electrospun” must be written as a single word. 
  • It is suggested to break the last sentence after “human model”. 

In the Conflict of Interest statement – 

  • There must be a “,” after closed. 

Author Info

Corresponding Author
Samuel George
Peripheral Nerve Fellow, University Hospitals Birmingham NHS Foundation Trust, UK

Article Info

Article Type
Case Report
Publication history
Received: Fri 20, Dec 2019
Accepted: Fri 03, Jan 2020
Published: Thu 30, Jan 2020
Copyright
© 2023 Samuel George. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.SCR.2020.01.02