Hemorrhage Hypotension Influences on Plasma Glucose Concentration: A New Approach for Evaluating Baroreflex Effects on Metabolic Adjustments

Hemorrhage Hypotension Influences on Plasma Glucose Concentration: A New Approach for Evaluating Baroreflex Effects on Metabolic Adjustments

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for


A: Good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Weak


Comments: The heading ‘Methods’ and ‘Conclusion’ has been incorporated.


Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good


Comments: The authors proposed the baroreflex control of the hyperglycemic response to hemorrhage as a reliable tool for evaluating the integration between cardiovascular and metabolic adjustments. It also gave an overview of the overall analysis of the research on the baroreflex curve to the heart rate.



Q: Does the author utilize relevant literature?

A: Good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good



Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good


Writing style

Q: Is it clear and understandable?

A: Good


Comments: There are few errors found in the manuscript, which are as follows:

·       Word ‘addition’ has been misspelled as ‘adittion’.

·       Under Abstract, 4th sentence, “In adittion, the baroreflex control to heart rate was assessed by…” is written as In addition, the baroreflex control of heart rate was assessed by…”.


Further comments on the paper

Comments: The manuscript illustrates a new approach for evaluating baroreflex effects on metabolic adjustments. It further put forth the outcome of the hypercaloric diet to the baroreflex curve, providing an explanation to the methods of research. The authors suggest that the baroreflex control of the hyperglycemic response is a useful tool for the evaluation of metabolic dysfunction related to hemorrhage.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Science Repository Team


Author Info

Corresponding Author
Cândido Celso Coimbra
Department of Physiology and Biophysics, Institute of Biological Sciences, Federal University of Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

Article Info

Article Type
Research Article
Publication history
Received: Thu 16, Jun 2022
Accepted: Fri 01, Jul 2022
Published: Mon 18, Jul 2022
© 2021 Cândido Celso Coimbra. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.JICOA.2022.02.03