Correlation Between Vitamin D and Degenerative Joint Disorders: Review and Meta-Analysis

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for researchers?

A: Good

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

Tools and Methods

Q: Are the methods the author uses adequate and well-used?

A: Good

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them coherent?

A: Very good

Comments:

In the present review, the methodology was performed according to the Cochrane Manual of Systematic Review. The Discussion puts forth the rationale for taking up the study, effectively describes the relevant literature and enlists the implications of the findings from the present study in that context. The study is well supported with briefly explained figures and tables. The Conclusion is consistent with the evidences presented in this article and aptly states that Vitamin D supplementation was effective in increasing vitamin D levels and improving pain, physical function and, to a lesser extent, stiffness in patients with symptomatic knee osteoarthritis.

Literature

Q: Does the author utilize relevant literature?

A: Very good

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

Length

Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

Writing style

Q: Is it clear and understandable?

A: Very good

Further comments on the paper

Comments: This study aims to undertake a systematic review and meta-analysis of randomized controlled studies (RCTs) to determine the efficacy of vitamin D supplementation in knee osteoarthritis (OA) symptoms and progression, compared with placebo. This study holds significance as vitamin D supplementation was effective in improving Western Ontario and McMaster Universities Arthritis Index (WOMAC) pain and function in patients with knee OA and also improved serological vitamin D levels. There are currently no medical treatments established to prevent the disease progression, only to control the symptomatology. The small sample size, inclusion of patients with sufficient vitamin D levels, duration of the intervention and inclusion of patients with advanced OA come out as few of the limitations of the included studies.

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions or clarifications you can write to the journal.

Thanks,
Science Repository Team