Comparison Between CT Volumetric Measurement and RECIST 1.1 Criteria to Assess the Tumoral Response in Advanced Renal Cell Carcinoma Treated by Immunotherapy

Comparison Between CT Volumetric Measurement and RECIST 1.1 Criteria to Assess the Tumoral Response in Advanced Renal Cell Carcinoma Treated by Immunotherapy

Review Data

Q: Is the topic relevant to the journal's area of interest? Is it contemporary and interesting for


A: Good


Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Good



Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Good



Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good


Tools and Methods

Q: Are the methods the author uses adequate and well used?

A: Good


Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good


Comments: The Discussion illustrates the comprehensive retrospective study conducted for the research providing relevant literature. The authors compared the previous reports with the results of the study and evaluated the reproducibility of the volumetry. Further, the Discussion puts forth the limitations of the research. The Conclusion summarizes that inter-observer reproducibility of the volumetric method is higher than RECIST measurements in advanced renal cancer.



Q: Does the author utilize relevant literature?

A: Good


Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good



Q: Is the paper's length adequate to the topic's significance? Do you suggest shortening the paper without losing its value?

A: Good


Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Good


Writing style

Q: Is it clear and understandable?

A: Good


Further comments on the paper

Comments: The manuscript establishes a retrospective comparison between the volumetric method versus gold standard unidimensional measurement based on RECIST 1.1 to assess the tumoral response in advanced renal cell carcinoma treated by immunotherapy. The research gave a detailed account of the population, CT acquisition, target lesion measurements, response assessment and statistical analysis.


Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

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Science Repository Team


Author Info

Corresponding Author
Catherine Roy
Department of Radiology B, University Hospital of Strasbourg – New Civil Hospital, Strasbourg, Cedex, France

Article Info

Article Type
Research Article
Publication history
Received: Sat 09, Jul 2022
Accepted: Mon 25, Jul 2022
Published: Fri 05, Aug 2022
© 2023 Catherine Roy. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2022.03.03