Advancements and Future Predictions on Diagnostic Approaches towards Cervical Cancer through Nanotechnology-Based Sensors for the Detection of Human Papillomavirus

Advancements and Future Predictions on Diagnostic Approaches towards Cervical Cancer through Nanotechnology-Based Sensors for the Detection of Human Papillomavirus

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

 

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

 

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

 

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Good

Comments:

The manuscript is mostly well-written except a few minor errors (already corrected in the galley proof), which are listed below:

  • In the 4th sentence of 2nd paragraph of Introduction, “There two main categories” should be corrected to “There are two main categories”.
  • The 2nd sentence of 3rd paragraph of Introduction should be reframed as, “A persistent infection by HPV can be developed by other factors like use of hormonal contraceptives, which can lead to cervical cancer in women”.
  • In the last sentence of 5th paragraph of Introduction, the word “analysis” should be replaced with “analyse”.
  • In the 2nd last line of Conclusion, the word “exiting” should be corrected to “existing”.

·       Punctuations and articles, e.g., “the” were missing in several places throughout the text.

 

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

 

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Very good

 

Comments:

This review summarizes the recent developments in the detection of cervical cancer using biosensors because of some loopholes existing in the present screening technologies available. The study discusses about the future aspects possible for the detection of cervical cancer using nanotechnology-based DNA-enabled sensors and their advantages over various conventional methods present currently. The review concludes that in the coming years, biosensors with nanomaterials can be a great assist in the detection of human papillomavirus at an early stage with greater precision.

 

Literature

Q: Does the author utilize relevant literature?

A: Very good

 

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Good

 

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

 

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

 

Writing style

Q: Is it clear and understandable?

A: Good

 

Further comments on the paper

Comments: This review outlines the current applications of biosensors for the diagnosis of human papillomavirus (HPV), as compared to the conventional techniques for measuring HPV that have some limitations. Cervical cancer has the highest mortality rate worldwide. Nanotechnology has emerged as a powerful diagnostic method for various cancers and is developing promising biosensor platforms for the ultrasensitive detection of HPV. The traditional methods used for cervical cancer are less sensitive, whereas nanotechnology has greatly improved the sensitivity. The conventional techniques for the detection of cervical cancer have some major drawbacks such as being expensive, long assessment duration, skilled professionals to handle the instrument. Therefore, the development of biosensor for the diagnosis of HPV is significant as it has explored new approaches leading to overcome these limitations.

 

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team

 
 

Author Info

Corresponding Author
Nidhi Chauhan
Amity Institute of Nanotechnology, Amity University Uttar Pradesh, Noida, India

Article Info

Article Type
Review Article
Publication history
Received: Sat 15, May 2021
Accepted: Tue 01, Jun 2021
Published: Fri 30, Jul 2021
Copyright
© 2023 Nidhi Chauhan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2021.06.02