Tissue Infiltrating Immune Cells and Endometrial Cancer Prognosis
Tissue Infiltrating Immune Cells and Endometrial Cancer Prognosis
Review Data
Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for
researchers?
A: Excellent
Abstract & Keywords
Q: Are all required components included in the abstract? Are the keywords appropriately chosen?
A: Very good
Goal
Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?
A: Good
Structure
Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?
A: Good
Tools and Methods
Q: Are methods the author uses adequate and well used?
A: Good
Discussion & Conclusion
Q: Is it related to the results presented before? Do you consider them as coherent?
A: Very good
Comments:
This review briefly discusses current knowledge in the area of immune cells and how they may alter the course of endometrial cancer (EC), as well as the implications of these cells for novel therapy and outcome. The study concludes in hope that the outcome of ongoing clinical trials and the design of novel clinical trials with combination treatment regimens in EC patients will significantly advance the field of EC therapy, and soon provide much needed translational options for patients with advanced/ metastatic EC, resulting in improved survival.
Literature
Q: Does the author utilize relevant literature?
A: Good
Author's knowledge
Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?
A: Very good
Length
Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?
A: Good
Figures & Tables
Q: Does the author use them suitably? Are legend and notations clear?
A: Good
Writing style
Q: Is it clear and understandable?
A: Good
Further comments on the paper
Comments: This review provides an understanding of the primary cell types in the endometrial cancer (EC) tumor microenvironment (TME) and briefly discusses how novel treatments may potentially modulate these cells to improve survival. The study holds significance as endometrial cancer (uterine corpus endometrial cancer) is the predominantly occurring female gynecologic cancer in the Western world. Even though there are a limited number of studies in the literature characterizing the TME of EC patients, it is evident that immune suppression in EC is multifaceted which further clues that a better understanding of the immune cells will result in improved and novel treatments for this disease.
Q: Would you recommend this manuscript for further publication?
A: Yes - Suitable to be published
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Author Info
Maureen Drakes Swati Mehrotra Ronald K. Potkul Cheryl M. Czerlanis Patrick J. Stiff
Corresponding Author
Maureen DrakesDepartment of Medicine, Cardinal Bernardin Cancer Center, Loyola University Chicago, Chicago, Illinois, USA
Article Info
Article Type
Review ArticlePublication history
Received: Fri 05, Mar 2021Accepted: Tue 23, Mar 2021
Published: Mon 19, Apr 2021
Copyright
© 2023 Maureen Drakes. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.DOI: 10.31487/j.COR.2021.04.01