Towards the Immunogenic Hyperthermic Action: Modulated ElectroHyperthermia
Towards the Immunogenic Hyperthermic Action: Modulated ElectroHyperthermia
Review Data
Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for
researchers?
A: Very good
Abstract & Keywords
Q: Are all required components included in the abstract? Are the keywords appropriately chosen?
A: Very good
Goal
Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?
A: Very good
Structure
Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?
A: Good
Comments: The heading “Results” should be replaced with “Discussion” as it sounds more appropriate and matches with the content present inside.
Tools and Methods
Q: Are methods the author uses adequate and well used?
A: Very good
Discussion & Conclusion
Q: Is it related to the results presented before? Do you consider them as coherent?
A: Very good
Comments:
The Results section thoroughly analyses the clinical benefits of modulated electro-hyperthermia (mEHT) in association with chemotherapy and radiotherapy in wide range of oncologic clinical applications. The Conclusion is consistent with the results presented in the article.
Literature
Q: Does the author utilize relevant literature?
A: Good
Author's knowledge
Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?
A: Very good
Length
Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?
A: Good
Figures & Tables
Q: Does the author use them suitably? Are legend and notations clear?
A: Insufficient
Writing style
Q: Is it clear and understandable?
A: Good
Further comments on the paper
Comments: This review article focuses on the efficacy and selectivity of modulated electro-hyperthermia (mEHT) to induce tumor cell death in cancer patients. This complementary treatment, together with chemotherapy and radiation therapy stands to be a significant technological advancement in the hyperthermia field, utilizing its electromagnetic power on the tumor cell membrane to induce drug delivery, increase the blood flow and oxygen radical production which results in massive apoptosis. Chemo-radiotherapy along with mEHT prolongs the overall survival time, suppresses the toxicity of the treatment and improves the quality of life of HIV-positive cervical cancer patients. The abscopal effect has proven to be a successful parameter in advanced cervical cancer treatment with mEHT which shows the effects of tumor-directed immunotherapy.
Q: Would you recommend this manuscript for further publication?
A: Yes - Suitable to be published
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Author Info
Corresponding Author
Andras SzaszProfessor, Chair, Department of Biotechnics, St. Istvan University, Hungary
Article Info
Article Type
Research ArticlePublication history
Received: Wed 19, Aug 2020Accepted: Tue 08, Sep 2020
Published: Fri 18, Sep 2020
Copyright
© 2023 Andras Szasz. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.DOI: 10.31487/j.COR.2020.09.07