The Significance of Inflammatory Markers in the Prognosis of Newly Diagnosed Multiple Myeloma Patients

The Significance of Inflammatory Markers in the Prognosis of Newly Diagnosed Multiple Myeloma Patients

Review Data

Q: Is the topic relevant to the journal area of interest? Is it contemporary and interesting for

researchers?

A: Excellent

 

Abstract & Keywords

Q: Are all required components included in the abstract? Are the keywords appropriately chosen?

A: Very good

 

Goal

Q: Is the goal explicitly stated in the Introduction? Is its formulation clear and unambiguous?

A: Very good

 

Structure

Q: Is the paper's structure coherent? Is it in coherence with the goal of the paper?

A: Very good

 

Tools and Methods

Q: Are methods the author uses adequate and well used?

A: Good

 

Discussion & Conclusion

Q: Is it related to the results presented before? Do you consider them as coherent?

A: Good

 

Comments:

The Results are well supported with figures and tables. The Discussion is consistent with the context of the study and explains how NLR and PLR are convenient and economical parameters, which can be used as prognostic indicators for newly diagnosed multiple myeloma. The pathophysiological mechanism of the association between NLR and PLR and poor prognosis of multiple myeloma is currently unknown; therefore further research is required in this field.

 

Literature

Q: Does the author utilize relevant literature?

A: Very good

 

Author's knowledge

Q: What is the level of the author’s knowledge? Does the author utilize all recent contributions relevant to the topic?

A: Very good

 

Length

Q: Is the length of the paper adequate to the significance of the topic? Do you suggest shortening the paper without losing its value?

A: Good

 

Figures & Tables

Q: Does the author use them suitably? Are legend and notations clear?

A: Very good

 

Writing style

Q: Is it clear and understandable?

A: Very good

 

Further comments on the paper

Comments: This retrospective study of 60 patients with multiple myeloma is significant since there are only few studies on the prognostic value of the ratio of neutrophils to lymphocytes (NLR), monocytes to lymphocytes (MLR), platelets to lymphocytes (PLR) and other inflammatory markers for newly diagnosed multiple myeloma. The existing research results are not uniform and till now, inflammatory markers have not been confirmed as the prognostic indicators of multiple myeloma. This study analyses the NLR, MLR, PLR, and other clinical and laboratory indicators of newly diagnosed multiple myeloma patients, along with their relationship with overall survival, and discusses the value of inflammatory markers in the prognosis of multiple myeloma patients.

 

Q: Would you recommend this manuscript for further publication?

A: Yes - Suitable to be published

If you have any questions and clarifications you can write to the journal.

Thanks,
Science Repository Team

 
 

Author Info

Corresponding Author
Baoan Chen
Department of Hematology and Oncology, Zhongda Hospital, School of Medicine, Southeast University, Nanjing, Jiangsu Province, China

Article Info

Article Type
Research Article
Publication history
Received: Tue 11, Aug 2020
Accepted: Tue 25, Aug 2020
Published: Tue 01, Sep 2020
Copyright
© 2023 Baoan Chen. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.09.01