Water-soluble SCR7 Can Abrogate DNA End Joining and Induce Cancer Cell Death

Water-soluble SCR7 Can Abrogate DNA End Joining and Induce Cancer Cell Death

Review Data


Purpose and Significance of Study: This study proposes the exciting possibility of using a water-soluble salt of SCR7, a hydrophobic small molecule inhibitor of non-homologous end joining of DNA, for cancer therapy.

 

Fit with Scope of Journal: The manuscript is of very high interest for the journal Clinical Oncology and Research.

 

The Results and Discussion lays down the results clearly and aptly explains their implications in cancer therapeutics with respect to the relevant data.

 

o   The manuscript contains a few minor errors (already corrected in the galley proof), listed below –

 

·       In the 4th sentence of the Abstract, “to” must be inserted after “referred”.

·       In the 4th sentence, “into” must be replaced with “in”, and “possess” must be replaced with “possesses”.

·       Omission of “the” in many places, e.g., before “current” in the 1st sentence of the Abstract, before “induction” in the last sentence of the Abstract, and so on.

·       Omission of “,”, e.g., before “thereby” in the 3rd sentence of the Abstract, after “years” in the 1st sentence in the 3rd paragraph of the Introduction, and so on.

Author Info

Corresponding Author
Sathees C. Raghavan
Department of Biochemistry, Indian Institute of Science, Bangalore, India

Article Info

Article Type
Research Article
Publication history
Received: Tue 09, Jun 2020
Accepted: Wed 01, Jul 2020
Published: Thu 16, Jul 2020
Copyright
© 2023 Sathees C. Raghavan. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.07.09