Liver Needle Biopsies are Poor Predictors of Histologic Tumor Grade for Midgut Neuroendocrine Tumors

Liver Needle Biopsies are Poor Predictors of Histologic Tumor Grade for Midgut Neuroendocrine Tumors

Review Data

Purpose and Significance of Study: This study aims to test the hypothesis that the preoperative needle biopsies are not reliable in predicting histologic tumor grade in midgut neuroendocrine tumors, by comparing with the corresponding surgical tissue. Despite the fundamental utility of this prediction method, the results confirm the suspicion, which, although not a novel finding, is significant, keeping in mind the recent studies to this end.   

 

Fit with Scope of Journal: The manuscript is of very high interest for the journal Clinical Oncology and Research. 

 

The manuscript is well-written and mostly error-free. A few minor errors (already incorporated in the galley proof) are listed below – 

 

·       A common error is omission of “the”, e.g. in the Background section of Abstract, in the last sentence, before “histologic grade”, in the Conclusion section of Abstract, in the 2nd sentence, before “actual clinical course”, and so on. 

 

In the Introduction section –  

  In the 2nd paragraph – 

·       In the 4th sentence, “outcome” must be replaced with outcomes. 

  In the 3rd paragraph – 

·       In the last sentence, “and that” must be inserted after “specimen”. 

 

In the Methods section – 

·       In the 3rd sentence, “that” must be replaced by “who”, “aspirate” must be replaced by “aspiration” and “(FNA)” must be inserted after “fine-needle aspirate”. 

 

In the Results section –  

·       In the 5th and 6th sentences, “in” after “observed discordance” must be replaced by “between”. 

 

In the Discussion section – 

  In the 1st paragraph – 

·       In the 3rd sentence, “Patient’s” must be replaced by “patients’”. 

·       In the 5th sentence, “grade” must be replaced by “grading”. 

  In the 2nd paragraph – 

·       In the 4th sentence, “grade” must be inserted before “(G3)”.

 

This study should be published for greater visibility of the scientific community. We recommend this for further publishing. All the best to the authors.     


If you have any questions and clarifications you can write to the journal.


Thanks,
Science Repository Team

 

 

 
 

Author Info

Corresponding Author
Robert A. Ramirez
Ochsner Medical Center, Kenner, LA, USA

Article Info

Article Type
Research Article
Publication history
Received: Fri 10, Jan 2020
Accepted: Wed 29, Jan 2020
Published: Fri 31, Jan 2020
Copyright
© 2023 Robert A. Ramirez. This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. Hosting by Science Repository.
DOI: 10.31487/j.COR.2020.01.07