Rwik Sen, Cancer and COVID-19: At Perilous Crossroads Clinical Oncology and Research 2021 2613-4942 http://dx.doi.org/10.31487/j.COR.2021.02.04 https://www.sciencerepository.org/cancer-and-covid-19-at-perilous-crossroads_COR-2021-2-104 Abstract: Cancer has been reported in several COVID-19 patients with varying outcomes. Clinical oncology and COVID-19 treatment are both severely challenged in those patients. Although, cancer was not considered among COVID-19 comorbidities, recent observations bring significant focus to cancer’s role in COVID-19 associated morbidity and mortality. Although the investigations in this direction are less in number, but the results show extremely interesting insights which can better inform the future diagnosis, treatment, and understanding of the pathophysiologies in cancers and COVID-19 in patients. Significant research, therapeutic developments, and treatment procedures need to be invested in this direction. Therefore, some of the current studies exploring this field have been presented in this mini-review.Keywords: COVID-19, cancer, comorbidity, immunity, risk factors, SARS CoV-2