Aditya Vishnu Pokala,Mabel Huai Bin Ko,Bo Shen, Successful Treatment of Prepouch Ileitis with Oral Mesalamine in Barnett Continent Ileal Reservoir Surgical Case Reports 2021 2613-5965 http://dx.doi.org/10.31487/j.SCR.2021.08.02 https://www.sciencerepository.org/successful-treatment-of-prepouch-ileitis_SCR-2021-8-102 Abstract: Barnett Continent Ileal Reservoir is rarely performed in patients with ulcerative colitis who require colectomy. Prepouch ileitis occasionally occurs in patients with ileal pouches. The role of oral mesalamine in the treatment of prepouch ileitis has not been established. We describe a case in which prepouch ileitis in Barnett Continent Ileal Reservoir was successfully treated with oral mesalamine. This is the first case in the literature showing that mesalamine is safe and effective in the treatment of prepouch ileitis in a patient with a continent ileostomy.Keywords: Barnett continent ileal reservoir, continent ileostomy, ileal pouch-anal anastomosis, mesalamine, treatment, prepouch ileitis