Suzanne  Beecher,Gráinne  Bourke,E Jason  Kelly,
Epoprostenol & Its Use in Microvascular Surgery – A Useful Aid to Flap Salvage Secondary to Recalcitrant Vasospasm?
Surgical Case Reports
2020
2613-5965
http://dx.doi.org/10.31487/j.SCR.2020.12.01
https://www.sciencerepository.org/epoprostenol-and-its-use-in-microvascular-surgery-a-useful-aid_SCR-2020-12-101 
Abstract: Systemic intravenous epoprostenol, as well as being a vasodilator, is the most potent inhibitor of platelet
aggregation known. Early research carried out on its use in microvascular surgery showed promising results
in preventing thrombosis and improving flap survival rates, however interest in its use in microsurgery has
diminished in recent years. In this report we describe its use in successful free flap salvage and discuss its
role in microsurgery.Keywords: Epoprostenol, flap salvage, vasospasm, microsurgery, thrombosis