Cortes  Andrés,Cubero  Alain,Hamzeh  Gadah,Rodríguez  Miguel A,Pérez  Clara,José  I. Aramendi,
Surgical Treatment of Abdominal Aortic Aneurysm in a 3-Year-Old Girl with Tuberous Sclerosis Complex
Surgical Case Reports
2020
2613-5965
http://dx.doi.org/10.31487/j.SCR.2020.08.19
https://www.sciencerepository.org/surgical-treatment-of-abdominal-aortic-aneurysm-in-a-3-year-old_SCR-2020-8-119 
Abstract: The tuberous sclerosis complex is a multisystem disorder affecting children and adults. The association
between abdominal aortic aneurysm and tuberous sclerosis is rare. We present 3-year-old girl with a
pulsatile abdominal mass in the pediatrician´s medical review. An abdominal evaluation showed a 6cm
infrarenal abdominal aortic aneurysm. The patient underwent open repair with a 14-mm Dacron tube graft.
The histological examination revealed connective tissue proliferation, fibrosis, and calcification of the aortic
wall. Frequent follow-ups with ultrasounds showed no alterations. Due to the high risk of rupture, early
surgical repair is the first-line therapy.Keywords: Tuberous sclerosis, abdominal aortic aneurysm, congenital heart disease (CHD), vascular disease, genetics