Alfredo Zucchi,Claudio Feliciani,Elena Pierobon,Michele Maria Dominici,Roberto D'Astolto, A Peculiar Way of Reconstruction for Surgical Defects of the Upper Lip: A Case Report Surgical Case Reports 2020 2613-5965 http://dx.doi.org/10.31487/j.SCR.2020.04.03 https://www.sciencerepository.org/a-peculiar-way-of-reconstruction-for-surgical-defects-of-the-upper-lip_SCR-2020-4-103 Abstract: Cutaneous neoformations of the upper lip, especially non melanoma skin cancers (NMSC), are very common. The upper lip is composed of multiple cosmetic subunits and it is divided into a philtral subunit and two lateral ones. For what concerns philtral subunit, Cupid’s bow can be particularly difficult to be recreated after a surgical excision. The vermillion border, that has the function to separate the inner surface of the lip (oral mucosa) from the surrounding skin, lies directly on a circumoral band of orbicularis oris. This is a circumferential muscle with a rich vascular supply that gives the lips their shape, definition and function. Any surgical wound of the lip can be repaired successfully in a variety of ways and the goal is always to maintain the integrity of the philtrum and the Cupid’s bow. We present the case of a 63 year-old woman with a pinkish nodule of the central portion of the upper lip, focusing on surgical reconstruction.Keywords: Surgery, dermatology, dermatologic surgery, flap, lip, reconstruction