Dominic Power,Samuel George,Ute Pohl,
Analysis of an End Neuroma 6 Months after Capping with a Bioresorbable Polycaprolactone Cap (NEUROCAP®) in a Human Model
Surgical Case Reports
2020
2613-5965
http://dx.doi.org/10.31487/j.SCR.2020.01.02
https://www.sciencerepository.org/analysis-of-an-end-neuroma-6-months_SCR-2020-1-102 
Abstract: Various methods have been described in the literature for the treatment of painful end neuromas. One
technique involves capping the neuroma with a biological or synthetic material. However, failure of this
technique may result from mechanical irritation of the capped nerve. In addition, the physical act of blocking
the nerve end is insufficient to prevent further neuroma formation and additional measures need to be taken
to halt the regenerative process of the nerve. A new technique of using a bioresorbable polycaprolactone
cap (NEUROCAP®), leaving a chamber distal to the nerve ending, has been studied in animal models. The
chamber results in a resultant thinner, cone shaped neuroma with a more organised fascicle structure. The
chamber prevents mechanical tether or compression by scar. The cap resorbs, preventing mechanical
irritation of the nerve ending. We present a case where a NEUROCAP® was excised 6 months after
implantation and the nerve end was studied. This study is the first of its kind, analysed in a human model.Keywords: Neuroma, neurocap, polycaprolactone, end neuroma, nerve cap, nerve, pain, polyganics