Schammel David,Christine Schammel,Krishna Yamuna,Schammel Joshua,Trocha Steven,Young Allison, The Great Imposture: Eosinophilic Cholangitis Surgical Case Reports 2018 2613-5965 http://dx.doi.org/10.31487/j.SCR.2018.03.013 https://www.sciencerepository.org/the-great-imposture-eosinophilic-cholangitis_SCR-3-113 Abstract: Eosinophilic Cholangitis (EC) is a rare, benign disease often mistaken for cholangiocarcinoma as clinically and radiologically EC resembles cholangiocarcinoma. Often, extensive hepatobiliary resections for a presumed malignancy are completed; however, with appropriate diagnosis EC can be managed medically. We present two cases of EC with a comprehensive literature review and a proposed diagnostic decision algorithm for EC by which to evaluate suspicious lesions with biliary obstruction and potentially avoid surgery for this benign disease.Keywords: biliary obstruction, benign liver disease, cholangiocarcinoma, diagnostic algorithm, malignant versus benign